Results 51 to 60 of about 75,382 (270)

Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species.

open access: yesPLoS ONE, 2017
It has been proposed that aging results from the lifelong accumulation of intracellular damage via reactions with reactive oxygen species (ROS). Metallothioneins are conserved cysteine-rich proteins that function as efficient ROS scavengers and may ...
Julie A Hall   +2 more
doaj   +1 more source

Tumor cell cytoplasmic metallothionein expression associates with differential tumor immunogenicity and prognostic outcome in high-grade serous ovarian carcinoma

open access: yesFrontiers in Oncology, 2023
BackgroundThe underlying mechanism of high T-cell presence as a favorable prognostic factor in high-grade serous ovarian carcinoma (HGSOC) is not yet understood. In addition to immune cells, various cofactors are essential for immune processes.
Elena Mairinger   +11 more
doaj   +1 more source

A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models [PDF]

open access: yes, 2020
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic homeostasis of this essential trace element. This review summarizes the key aspects of human zinc homeostasis and distribution.
Haase, Hajo, Maares, Maria
core   +1 more source

Metallothionein '96

open access: yesJournal of UOEH, 1997
Metallothionein (MT) has been considered to play important roles in metal homeostasis and also in protecting against metal toxicities. There are four MT isoforms in mammalian cells. Recent studies using MT-I and -II genes knockout mice demonstrated that MT-I and -II are mainly involved in the protection against metal toxicities, oxidative stresses, and
openaire   +3 more sources

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan   +5 more
wiley   +1 more source

Nuclear metallothionein in oral squamous cell carcinoma: clinicopathological parameters and patient survival

open access: yesBrazilian Oral Research, 2018
The aim of this study was to identify the immunoexpression of methallothionein in oral squamous cell carcinoma as well as to address the correlation with clinical features, histological grade and patient survival.
Girlene Maria do Rego BEZERRA   +6 more
doaj   +1 more source

Metallothionein as an indicator of water quality: assessment of the bioavailability of cadmium, copper, mercury and zinc in aquatic animals at the cellular level [PDF]

open access: yes, 1994
The study of metallothioneins (MTs) has greatly improved our understanding of body burdens, metal storage and detoxification in aquatic organisms subjected to contamination by the toxic heavy metals, Cd, Cu, Hg and Zn.
George, S.G., Langston, W.J.
core  

Influence of Zn2+ and Oxygen Supply on Malic Acid Production and Growth of Aspergillus oryzae

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Malic acid is a valuable platform chemical traditionally derived from fossil‐based resources. Microbial cultivation with Aspergillus oryzae offers a sustainable alternative based on renewable feedstocks. In this study, a well‐established minimal medium for malic acid production, commonly used in previous research to ensure reproducibility, was
Lukas Hartmann   +3 more
wiley   +1 more source

Comparison of RCAS1 and metallothionein expression and the presence and activity of immune cells in human ovarian and abdominal wall endometriomas

open access: yesReproductive Biology and Endocrinology, 2006
Background The coexistence of endometrial and immune cells during decidualization is preserved by the ability of endometrial cells to regulate the cytotoxic immune activity and their capability to be resistant to immune-mediated apoptosis.
Lazar Agata   +6 more
doaj   +1 more source

Release of mercury from amalgam filling and its relationship with metallothionein and superoxide dismutase

open access: yesEuropean Oral Research, 2023
Purpose This study aims at determining the amount of mercury released over time from amalgam after treatment in healthy subjects and to examine the relation of mercury with serum MT-1 and SOD-1 levels. Materials and Methods Amalgam filling was applied to
Pınar Gül   +5 more
doaj   +1 more source

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