Results 51 to 60 of about 30,614 (220)
Evaluation of Hybridoma B9 cell line handling of Cadmium in the presence of Interleukin-6
Journal of Applied Sciences and Environmental Management, 2005 Induction of metallothionein synthesis in the presence or absence of Interleukin –6 (IL-6) was one of the responses examined to identify the mechanism by which IL-6 (at high concentration) was able to reverse cadmium inhibition of B9 cell line ...
I Orupabo
doaj +1 more source
Metallothioneins, a Part of the Retinal Endogenous Protective System in Various Ocular Diseases
Antioxidants, 2023 Metallothioneins are the metal-rich proteins that play important roles in metal homeostasis and detoxification. Moreover, these proteins protect cells against oxidative stress, inhibit proapoptotic mechanisms and enhance cell differentiation and survival.
Daniel Jamrozik +5 more
doaj +1 more source
Exploration, EarlyView.BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding +9 more
wiley +1 more source
Mutations in GFAP Alter Early Lineage Commitment of Organoids
Glia, EarlyView.Mutations in GFAP alter lineage commitment of organoids. The severity of this commitment defect is dependent on the method of embryoid body formation. GFAP is expressed in iPSCs and during early stages of organoid development. Graphical abstract was created with BioRender.com .
Werner Dykstra +14 more
wiley +1 more source
The multipotent role of metallothionein in the nervous system
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2013 We provide a commentary on current experimental and theoretical advances and frame our consideration in terms of the possible functions of MT I+II in the nervous system.
G. А. Ushakova, Y. P. Kovalchuk
doaj +1 more source
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Glia, EarlyView.Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa +7 more
wiley +1 more source
Epithelial–Mesenchymal Transition in Human Alveolar Cells Exposed to Indium Chloride
Journal of Applied Toxicology, EarlyView.ABSTRACT For workers in the industry, occupational exposure to indium compounds induces pulmonary disorders, such as interstitial pneumonia. Moreover, lung cancer has been reported in both humans and rodents exposed to indium compounds by inhalation. However, the biological mechanism underlying indium‐induced disorders is poorly understood.
Eiki Kimura +3 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT In recent decades, rising industrial demand for palladium (Pd), driven by its unique properties and affordability compared to other noble metals, has increased its environmental release into aquatic systems. This highlights the need to assess its effects on organisms, given the lack of standardized toxicity studies and regulations for this ...
Rania Boukhari +4 more
wiley +1 more source
Біологічні студії, 2012 Cis-dichlorodiammineplatinum (II), commonly known as cisplatin, is a widely used anticancer drug. However, the therapeutic efficacy of the drug is limited due to various dose-limiting side effects and development of acquired resistance. The resistance of
H. Falfushynska +3 more
doaj +1 more source
Targeted Intracellular Copper Reservoir Enhances Liver Cancer Immunotherapy
Small, EarlyView.Sono‐activatable TPEN‐encapsulated cancer‐targeted nanoparticles (STCNs) with sonodynamic therapy (SDT)‐amplified immunotherapeutic properties for liver cancer treatment via endogenous cuproptosis are developed. STCNs can effectively treat liver cancer through endogenous cuproptosis by TPEN and ROS generated by SDT, resulting in increased immune ...
Tianao Xie +15 more
wiley +1 more source