Results 61 to 70 of about 45,778 (231)
Characterization of a type 3 metallothionein isolated from Porteresia coarctata
Metallothioneins are involved in detoxification of heavy metals. A cDNA encoding type 3 metallothionein (PcMT3) was isolated from the salt stressed leaf cDNA library of Porteresia coarctata (Roxb.) Tateoka (wild rice) that grows well in the heavy metal ...
A. Parida +4 more
core +1 more source
Metallothionein in human oesophagus, Barrett's epithelium and adenocarcinoma [PDF]
© 2002 Cancer Research, UKThe potential of the metal-binding protein, metallothionein, in assessing the progression of normal oesophagus through Barrett's to adenocarcinoma was investigated.
G G Jamieson +13 more
core +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Metallothionein (MT) has been considered to play important roles in metal homeostasis and also in protecting against metal toxicities. There are four MT isoforms in mammalian cells. Recent studies using MT-I and -II genes knockout mice demonstrated that MT-I and -II are mainly involved in the protection against metal toxicities, oxidative stresses, and
openaire +3 more sources
Peran Metallothionein Terhadap Kemampuan Resistensi Logam Berat Pada Bakteri [PDF]
Saat ini pencemaran lingkungan yang terjadi mencapai tahap yang mengkhawatirkan. Industri merupakan salah satu faktor yang menyumbang polusi dan mengakibatkan pencemaran di dunia.
Ir. Aji Sutrisno, M. Sc, Ph. D +1 more
core
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves +8 more
wiley +1 more source
ABSTRACT Metal contamination in aquatic ecosystems poses substantial risks to freshwater organisms, with mixture effects often deviating from predictions based on single‐metal toxicity. Understanding how age‐specific sensitivities and multiple exposure pathways influence mixture effects is critical for accurate risk assessment.
Sanah Majid +3 more
wiley +1 more source
Background and Design.- Histopathological alterations to various organs of the different species in acute and chronic cadmium exposure have been studied by light and electron microscopy. Metallothionein is a protein inducible by heavy metal ions. The aim
Ömür KARABULUT-BULAN +4 more
doaj
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane +8 more
wiley +1 more source
This study investigated gene expression of drug resistance factors in biopsy tissue samples from hepatocellular carcinoma (HCC) patients undergoing chemotherapy by platinum complex. Liver biopsy was performed to collect tissue from the tumor site (T) and
Shiro Ueda +6 more
doaj +1 more source

