Results 81 to 90 of about 77,240 (295)

Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The human placenta not only detects the presence of Pb and Cd but also carries hypoxia and inflammatory risks, which are associated with pregnancy complications. To understand the impact of these factors on the placental trophoblast, we evaluated the effect of Pb and Cd on mitochondrial function and the NLRP3 inflammasome in ...
Yifeng Dai   +4 more
wiley   +1 more source

Cadmium in newborns [PDF]

open access: yes, 2003
Cadmium (Cd) is a well-known nephrotoxic environmental contaminant but there are indications that the developing nervous system might be even more sensitive to Cd than the kidneys in adults.
Eklund, Gunilla
core  

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength [PDF]

open access: yes, 2015
Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic mice
Chavassieux, P   +10 more
core   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian   +16 more
wiley   +1 more source

The multipotent role of metallothionein in the nervous system

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2013
We provide a commentary on current experimental and theoretical advances and frame our consideration in terms of the possible functions of MT I+II in the nervous system.
G. А. Ushakova, Y. P. Kovalchuk
doaj   +1 more source

Importance of Minerals and Their Bioavailability in Boosting Aquaculture: A Systematic Review

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.
ABSTRACT Fish like other terrestrial animals, have specific requirements for individual minerals that support the growth and maintenance of normal fish health and other biological functions among different cultured fish species. These minerals can be either macro or micro minerals that are supplied to the fish body through diets or absorbed from their ...
Francis Pius Mmanda
wiley   +1 more source

Expression of Drug-Resistant Factor Genes in Hepatocellular Carcinoma Patients Undergoing Chemotherapy with Platinum Complex by Arterial Infusion

open access: yesPharmaceutics, 2010
This study investigated gene expression of drug resistance factors in biopsy tissue samples from hepatocellular carcinoma (HCC) patients undergoing chemotherapy by platinum complex. Liver biopsy was performed to collect tissue from the tumor site (T) and
Shiro Ueda   +6 more
doaj   +1 more source

Copper Tolerance Mediated by FgAceA and FgCrpA in Fusarium graminearum

open access: yesFrontiers in Microbiology, 2020
All organisms must secure essential trace elements (e.g., Cu) for survival and reproduction. However, excess trace element accumulation in cells is highly toxic. The maintenance of copper (Cu) homeostasis has been extensively studied in mammals, bacteria,
Xin Liu   +15 more
doaj   +1 more source

Heavy Metal Pollution From Illegal Mining ‘Galamsey’ Activities on the Viability of Clarias gariepinus in the Oda River, Ghana

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.
ABSTRACT Activities associated with illegal mining, ‘galamsey’, often result in significant environmental degradation, particularly to water bodies. In the case of River Oda, like all other affected areas in Ghana, galamsey operations contribute to the pollution of the water body with some heavy metals such as mercury (Hg), cadmium (Cd) and arsenic (As)
Seth Adusei   +5 more
wiley   +1 more source

Cardiac-Specific Overexpression of Metallothionein Rescues against Cigarette Smoking Exposure-Induced Myocardial Contractile and Mitochondrial Damage

open access: yesPLoS ONE, 2013
Objectives Second hand cigarette smoke is an independent risk factor for cardiovascular disease. Although a tie between smoking and cardiovascular disease is well established, the underlying mechanisms still remains elusive due to the lack of adequate ...
N. Hu   +5 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy