Results 61 to 70 of about 831,785 (310)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Development in the drawing of metals Proceedings of the international conference [PDF]

, 1983
SIGLEAvailable from British Library Document Supply Centre- DSC:5699.468(301) / BLDSC - British Library Document Supply CentreGBUnited ...
Metals Society, London (United Kingdom), Metals Society, London (UK)   +1 more
core  

Ventilation and air conditioning design approach based on ASHRAE psychrometric chart and Mollier diagram

Frontiers in Built Environment
Society needs long-term sustainability and healthy building projects, and indoor air quality assurance engineering systems play a pivotal role in the energy performance of buildings.
Arturs Lešinskis, Uldis Strauts, Mārtiņš Metāls, Renārs Millers, Viktors Afoņičevs   +4 more
doaj   +1 more source

The Effect of Extrusion Parameters on Possibility of Extrusion of Magnesium Alloys in Continuous Rotary Extrusion Process / Wpływ Parametrów Procesu Wyciskania Na Możliwość Wyciskania Stopów Magnezu Metodą Ciągłego Wyciskania Na Kole

Archives of Metallurgy and Materials, 2015
Continuous rotary extrusion (CRE) is the more and more frequently used variation of the plastic working process. Magnesium alloys, due to its properties are becoming increasingly popular as a substitute for aluminium alloys and steel, particularly in the
Mitka M., Gawlik M., Bigaj M., Szymański W.   +3 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The corrosion behaviour of nanograined metals and alloys [PDF]

, 2012
There has been considerable interest in the properties of nanocrystalline materials over the last decade. Such materials include metals and alloys with a crystal size within the order of 1 to 100 nm. The interest arises due to the substantial differences
Ponce de Leon, Carlos, Herrasti Gonzalez, P., Walsh, F.C.   +2 more
core   +2 more sources

Studies of the AA2519 Alloy Hot Rolling Process and Cladding with EN AW-1050A Alloy

Archives of Metallurgy and Materials, 2016
The objective of the study was to determine the feasibility of plastic forming by hot rolling of the AA2519 aluminium alloy sheets and cladding these sheets with a layer of the EN AW-1050A alloy.
Płonka B., Rajda M., Zamkotowicz Z., Żelechowski J., Remsak K., Korczak P., Szymański W., Snieżek L.   +7 more
doaj   +1 more source

Metallic hydrogen [PDF]

Journal of Physics: Condensed Matter, 2018
Abstract Hydrogen is the simplest and most abundant element in the Universe. There are two pathways for creating metallic hydrogen under high pressures. Over 80 years ago Wigner and Huntington predicted that if solid molecular hydrogen was sufficiently compressed in the T   =
Ranga Dias, Isaac Silvera
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Fabrication and mechanical properties of porous tantalum carbon composites by chemical vapor deposition

Scientific Reports
This study investigates the deposition of tantalum (Ta) coatings on carbon foams using the chemical vapor deposition (CVD) method to enhance their compressive strength.
Junyu Zhu, Wenting Li, Hongzhong Cai, Xian Wang, Xingqiang Wang, Wuxun Zhu, Yan Wei, Xuming Li, Xingdong Zhao, Guixue Zhang, Haohong Jiang   +10 more
doaj   +1 more source