Results 131 to 140 of about 9,301 (237)

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

open access: yes, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania   +19 more
core   +1 more source

Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model

open access: yes, 2018
Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life.
Elsadek, Bakheet, Maqboul, Ahmad
core   +2 more sources

Tramadol and M1 Bioavailability Induced by Metamizole Co-Administration in Donkeys (Equus asinus)

open access: yesAnimals
Simple Summary The combination of an opioid compound with a nonsteroidal anti-inflammatory drug can lead to additive or enhanced effects while minimizing adverse reactions.
G. Araújo-Silva   +7 more
semanticscholar   +1 more source

Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review

open access: yesJournal of Clinical Medicine
Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties. Despite being in use since the 1920s, its mechanism of action still needs
Naveen Jeyaraman   +6 more
semanticscholar   +1 more source

The effect of metoclopramide on the antinociceptive, locomotor and neurobehavioral effects of metamizole in mice

open access: yesMacedonian Veterinary Review
Combining analgesic medications with distinct pharmacodynamics may result in effective analgesia and reduced adverse effects by lowering dosages of one or both medications. The objective was to investigate the nature of interactions of metoclopramide and
Zena Sattam Hamed   +2 more
doaj   +1 more source

Metamizole outperforms meloxicam in sepsis: insights on analgesics, survival and immunomodulation in the peritoneal contamination and infection sepsis model

open access: yesFrontiers in Immunology
Background Limited availability and side effects of opioids have led to an increased use of non-opioid analgesia in animal disease models. However, by affecting the immune-inflammatory reactions, analgesia may disrupt the resolution of the host ...
Na Liu   +9 more
semanticscholar   +1 more source

Dipyrone (metamizole)

open access: yes, 2018
Dipyrone (metamizole) is a non-opioid analgesic commonly used in Germany, which can, in very rare cases, cause life-threatening agranulocytosis. The prescribing information calls for regular monitoring of the differential blood count in cases of long-term treatment.
Stamer, Ulrike M.   +6 more
openaire   +1 more source

Postoperative Pain Management with Metamizole after Orthopedic Surgery: A Systematic Review

open access: yesKansas journal of medicine
Introduction Postoperative pain control is critical in orthopedic surgery. While efficacious analgesics, opiates have rapid tolerance and addictive potential. Metamizole is a non-opioid analgesic that primarily works by inhibiting COX-3, commonly used in
Michael Braman   +4 more
semanticscholar   +1 more source

Metamizol [PDF]

open access: yes, 2018
C. Vidal, W. -R. Külpmann
openaire   +1 more source

Adverse effects of metamizole on heart, lung, liver, kidney, and stomach in rats

open access: yesBMC Pharmacology and Toxicology
Metamizole is banned in some countries because of its toxicity, although it is widely used in some European countries. In addition, there is limited information on its safety profile, and it is still debated whether it is toxic to the heart, lungs, liver,
Sedat Çiftel   +9 more
semanticscholar   +1 more source

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