Results 121 to 130 of about 8,395 (267)

Potential Cytoprotective and Anti-Apoptotic Effect of Metamizole Alone and in Combination with Cytostatic Drugs Observed In Vitro in Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

Biomedicines
Metamizole (dipyrone) is still a frequently used drug in human and veterinary medicine, especially for pain relief, sometimes also in osteosarcoma treatment.
Dominik Poradowski, Aleksander Chrószcz, Radosław Spychaj, Vedat Onar   +3 more
doaj   +1 more source

Influence of Nonopioid Analgesics on Healthy Nucleus Pulposus Cells

Global Spine Journal, 2014
Introduction Recent advances in our understanding of intervertebral disc biology led to an increased interest in the development of cell transplantation therapies.
C. Eder, J. Trifinopoulos, S. Schildboeck, N. Koppensteiner, J. Zolles, E. Falkner, M. Ogon   +6 more
doaj   +1 more source

Evaluasi Rasionalitas Penggunaan Antibiotik Pada Pasien Sepsis Di Intensive Care Unit (Icu) RSUD Dr. Moewardi Surakarta Tahun 2016-2017 [PDF]

, 2018
Sepsis is one of the main causes of patients entering Intensive Care Unit (ICU) and is the cause of mortality in ICU space. Therapy with antibiotics is one of the supporting factors for success in the treatment of sepsis. This study was aimed to evaluate
, Ambar Yunita Nugraheni, M.Sc., Apt, Widya Rukmana, Restiana   +1 more
core  

The effect of metoclopramide on the antinociceptive, locomotor and neurobehavioral effects of metamizole in mice

Macedonian Veterinary Review
Combining analgesic medications with distinct pharmacodynamics may result in effective analgesia and reduced adverse effects by lowering dosages of one or both medications. The objective was to investigate the nature of interactions of metoclopramide and
Zena Sattam Hamed, Khalid Ahmed Shaban, Ghada Abdul-Munem Faris   +2 more
doaj   +1 more source

Fatal agranulocytosis associated with Metamizole treatment in a 16-year-old girl [PDF]

, 2019
PD Saint-Cyr Sylvestre, ND Clotaire, N’dhatz Comoe Emeraude, Boidy Kouakou, C Magloire, D Mamady, Mbelesso Pascal, KK Gustave   +7 more
openalex   +1 more source

Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study [PDF]

, 2019
Victoria C. Ziesenitz, Frédérique Rodieux, Andrew Atkinson, Carole Borter, Julia Bielicki, Manuel Haschke, Urs Duthaler, Fabio Bachmann, Thomas O. Erb, Nicolas Gürtler, Stefan Holland‐Cunz, Johannes N. van den Anker, Verena Gotta, Marc Pfister   +13 more
openalex   +1 more source

Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis

Molecules
Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis and potential hepatotoxicity.
Georgiana-Iulia Lupu, Emoke Pall, Mihai Cenariu, Monica Irina Nan, Sanda Andrei   +4 more
doaj   +1 more source

Dipyrone (metamizole)

, 2018
Dipyrone (metamizole) is a non-opioid analgesic commonly used in Germany, which can, in very rare cases, cause life-threatening agranulocytosis. The prescribing information calls for regular monitoring of the differential blood count in cases of long-term treatment.
Stamer, Ulrike M., Gundert-Remy, Ursula, Biermann, E., Erlenwein, Joachim, Meissner, W., Wirz, Stefan, Stammschulte, T.   +6 more
openaire   +1 more source

Agranulocytosis attributed to metamizole: An analysis of spontaneous reports in EudraVigilance 1985‐2017 [PDF]

, 2019
Falk Hoffmann, Carsten Bantel, Kathrin Jobski   +2 more
openalex   +1 more source

Metamizole Has Been Overlooked as a Trigger for Acute Liver Injury and Acute Liver Failure

, 2020
Marcial Sebode, Ansgar W. Lohse, Christoph Schramm   +2 more
openalex   +2 more sources