Results 41 to 50 of about 3,194,829 (296)

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]

open access: yes, 2013
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Brown, Euan R.   +2 more
core   +1 more source

TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila [PDF]

open access: yes, 2013
TDP-43 proteinopathy is strongly implicated in the pathogenesis of amyotrophic lateral sclerosis and related neurodegenerative disorders. Whether TDP-43 neurotoxicity is caused by a novel toxic gain-of-function mechanism of the aggregates or by a loss of
Adachi, Yoshitsugu   +13 more
core   +3 more sources

Sequencing and de novo analysis of Crassostrea angulata (Fujian oyster) from 8 different developing phases using 454 GSFlx. [PDF]

open access: yesPLoS ONE, 2012
Research on the mechanism for early development of shellfish, such as body plan, shell formation, settlement and metamorphosis is currently an active research field.
Ji Qin   +5 more
doaj   +1 more source

Gut microbial ecology of Xenopus tadpoles across life stages

open access: yesPeer Community Journal, 2021
Background: The microorganism world living in amphibians is still largely under-represented and under-studied in the literature. Among anuran amphibians, African clawed frogs of the Xenopus genus stand as well-characterized models with an in-depth ...
Scalvenzi, Thibault   +3 more
doaj   +1 more source

Human development II: We Need an Integrated Theory for Matter, Life and Consciousness to Understand Life and Healing

open access: yesThe Scientific World Journal, 2006
For almost a decade, we have experimented with supporting the philosophical development of severely ill patients to induce recovery and spontaneous healing.
Sören Ventegodt   +4 more
doaj   +1 more source

Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism

open access: yesBMC Molecular and Cell Biology, 2021
Background Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. A well-described function of apoptosis is the removal of excessive cells during development and homeostasis.
Gabriel Krasovec   +3 more
doaj   +1 more source

Potential of Oscheius tipulae nematodes as biological control agents against Ceratitis capitata

open access: yesPLoS ONE, 2022
A survey to collect soil nematodes with potential to control Ceratitis capitata flies was carried out in different locations in Tunisia. Several nematode isolates were recovered, laboratory colonies were established, and their taxonomic identities were ...
A. Loulou   +6 more
semanticscholar   +1 more source

Genome-Wide Analysis of MicroRNAs in Relation to Pupariation in Oriental Fruit Fly

open access: yesFrontiers in Physiology, 2019
Insect metamorphosis is a complex process involving drastic morphological and physiological changes. microRNAs (miRNAs) are a class of endogenous small non-coding RNAs that play key roles in regulating various biological processes, including ...
Qiang Zhang   +27 more
doaj   +1 more source

miRNAs of Aedes aegypti (Linnaeus 1762) conserved in six orders of the class Insecta

open access: yesScientific Reports, 2021
Aedes aegypti L. is the most important vector of arboviruses such as dengue, Zika, chikungunya, Mayaro, and yellow fever, which impact millions of people’s health per year.
Iram Pablo Rodríguez-Sanchez   +15 more
doaj   +1 more source

Growth and the expression of alternative life cycles in the salamander \u3ci\u3eAmbystoma talpoideum\u3c/i\u3e (Caudata: Ambystomatidae) [PDF]

open access: yes, 2003
Complex life cycles (CLCs) contain larval and adult phases that are morphologically and ecologically distinct. Simple life cycles (SLCs) have evolved from CLCs repeatedly in a wide variety of lineages but the processes that may underlie the transition ...
Ryan, Travis J, Semlitsch, Raymond D.
core   +1 more source

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