Results 221 to 230 of about 9,281 (248)

Interpret metanephrine results in light of clinical indications

BMJ, 2012
Jones and colleagues highlight the importance of making the diagnosis of phaeochromocytoma.1 We support their approach of initially undertaking biochemical investigations, but they do not deal clearly with sampling, patient preparation, and clinical indications for the test, which are essential for interpreting results.
Stewart J, Pattman, Andrew, Davison, Steve, Ball   +2 more
openaire   +2 more sources

A modified procedure for determining metanephrines in urine

Clinical Biochemistry, 1976
We have modified the procedure for determining total metanephrines in urine described by Gupta, Price and Keane(1) to shorten the time necessary for completion while allowing the technician time to perform other tests. The modification involves the extraction of interfering substances from urine. Instead of having to extract 3 individual tubes for each
T W, Fendley, C S, Frings
openaire   +2 more sources

Seasonal variation of urinary excretion of total metanephrines

Clinica Chimica Acta, 1976
Results of 1414 measurements of urinary excretion of free and conjugated (total) metanephrine and normetanephrine (total metanephrines, tMN) and of 1630 measurements of vanilmandelic acid (VMA) excretion were analysed according to the month of sample collection.
T, Yamamoto, K, Doi, Y, Takeuchi, M, Baba, M, Tanaka   +4 more
openaire   +2 more sources

Plasma free metanephrines for diagnosis of neuroblastoma patients

Clinical Biochemistry, 2019
A substantial number of patients with neuroblastoma (NB) have increased excretion of catecholamines and metanephrines. Here, we have investigated the diagnostic role of plasma free metanephrines (PFM), metanephrine (MN), normetanephrine (NMN) and 3-methoxytyramine (3MT) for NB, the most common extra-cranial solid tumour in children.PFM were quantified ...
Sebastiano Barco, Iedan Verly, Maria Valeria Corrias, Stefania Sorrentino, Massimo Conte, Gino Tripodi, Godelieve Tytgat, André van Kuilenburg, Maria van der Ham, Monique de Sain-van der Velden, Alberto Garaventa, Giuliana Cangemi   +11 more
openaire   +2 more sources

Falsely elevated plasma metanephrine in patients taking midodrine

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2018
Plasma metanephrines have become the biochemical test of choice for suspected phaeochromocytomas and paragangliomas in many institutions. We encountered two separate cases of significantly elevated plasma metanephrines in patients taking midodrine, a sympathomimetic drug used in the treatment of severe postural hypotension, in the absence of a ...
Holly Emms, George Farah, Brian Shine, Chris Boot, Barry Toole, Martin McFadden, Leo Lam, Zong-Quan Ou, Gerald Woollard, Hima Madhavaram, Campbell Kyle, Ashley B Grossman   +11 more
openaire   +2 more sources

Development of Enantioselective Immunoassays for Free Plasma Metanephrines

Annals of the New York Academy of Sciences, 2004
Abstract: The development of an enantioselective radioimmunoassay (RIA) and enzyme immunoassay (EIA) for L‐normetanephrine (NM) and L‐metanephrine (M) were studied. Prior to the immunoassay, the protein matrix of the ethylenediaminetetraacetic acid (EDTA) plasma samples was removed by acid precipitation, followed by derivatization of the L ...
Bernhard, Manz, Matthias, Kuper, Essy, Booltink, Ulrich, Fischer-Brügge   +3 more
openaire   +2 more sources

Quantitative Determination of Metanephrine and Normetanephrine in Urine

1966
Details of a fluorometric method for the separate determination of free and conjugated metanephrine and normetanephrine in urine are presented. The procedure consists of: (1) a separation and concentration of free amines by absorption on a column of Dowex-50 resin followed by elution with a small volume of aqueous ammonia; (2) acid hydrolysis of the ...
K, TANIGUCHI, Y, KAKIMOTO, M D, ARMSTRONG   +2 more
openaire   +2 more sources

Metanephrine normal, DOTATATE negative paraganglioma of the urinary bladder

BMJ Case Reports
A woman in her 30s presented with recurrent haematuria and dysuria for 1 year. Imaging revealed a 10 cm pedunculated mass in the bladder, with histopathology confirming paraganglioma. Initial management involved a transurethral biopsy of the tumour, followed by partial cystectomy with ureteric reimplantation.
Balabhaskar H, Namvir Meshram, Tony Thomas, Haris C H   +3 more
openaire   +2 more sources

Enzymic conversion of metanephrine to epinephrine

Biochimica et Biophysica Acta, 1958
J, AXELROD, S, SZARA
openaire   +2 more sources

A Negative Internal Standard in Urinary Metanephrines Quantification

Clinical Chemistry, 2022
Hugo, Alarcan, Arthur, Wilhelm, Colette, Faideau, Jean-Baptiste, Delaye, Christian R, Andres   +4 more
openaire   +2 more sources