Results 11 to 20 of about 6,958 (252)

Biochemical Diagnosis of Phaeochromocytoma and Paraganglioma in Children and Adolescents: A Retrospective Cohort Study. [PDF]

Clin Endocrinol (Oxf)
ABSTRACT Introduction Currently, it is unclear whether plasma free or 24‐h urinary fractionated metanephrines are preferable for diagnosis of phaeochromocytoma/paraganglioma (PPGL) in children. Objectives To investigate whether measurements of plasma free and 24‐h urinary fractionated metanephrines are reliable tests for screening for PPGL in children.
Potthoff K, Prodanov T, Knigge LM, Hübner A, Bornstein S, Lenders J, Pacak K, Eisenhofer G, Pamporaki C.   +8 more
europepmc   +2 more sources

Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension

Frontiers in Endocrinology, 2022
IntroductionNeuroblastoma (NB) is a pediatric cancer of the developing sympathetic nervous system. It produces and releases metanephrines, which are used as biomarkers for diagnosis in plasma and urine. However, plasma catecholamine concentrations remain
Annick Mühlethaler-Mottet, Silvia Uccella, Silvia Uccella, Deborah Marchiori, Stefano La Rosa, Stefano La Rosa, Jean Daraspe, Katia Balmas Bourloud, Maja Beck Popovic, Philippe J. Eugster, Eric Grouzmann, Karim Abid   +11 more
doaj   +1 more source

Non‐Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor [PDF]

IJU Case Rep
ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally.
Wainstein M, Aslot V, Dennie F, Wainstein M, Chandrasekar T.   +4 more
europepmc   +2 more sources

Unilateral and Bilateral Adrenalectomy for Pheochromocytoma Requires Adjustment of Urinary and Plasma Metanephrine Reference Ranges [PDF]

, 2013
Context: Follow-up after adrenalectomy for pheochromocytoma is recommended because of a recurrence risk. During follow-up, plasma and/or urinary metanephrine (MN) and normetanephrine (NMN) are interpreted using reference ranges obtained in healthy ...
Thamara E. Osinga, Maartje H. A. van den Eijnden, Ido P. Kema, Michiel N. Kerstens, Robin P. F. Dullaart, Wilhelmina H. A. de Jong, Wim J. Sluiter, Thera P. Links, Anouk N.A. van der Horst‐Schrivers   +8 more
openalex   +5 more sources

Quantitative Measurement of Plasma Free Metanephrines by a Simple and Cost-Effective Microextraction Packed Sorbent with Porous Graphitic Carbon and Liquid Chromatography-Tandem Mass Spectrometry

Journal of Analytical Methods in Chemistry, 2021
Plasma free metanephrines are widely used for the diagnosis of pheochromocytoma and paraganglioma (PPGL), yet quantifying metanephrines using a simple and cost-effective approach may be challenging due to preanalytical and analytical constraints. In this
Xin Xiong, Yuanyuan Zhang, Rongsheng Zhao   +2 more
doaj   +1 more source

Stress biomarkers in adult patients with drug‐resistant epilepsy on a modified Atkins diet: A prospective study

Epilepsia Open, 2023
Objective Ketogenic diets like the modified Atkins diet (MAD) are increasingly used in patients with refractory epilepsy. For epilepsy patients, stress is a well‐known seizure‐precipitating factor. New possibilities for measuring biomarkers of stress are
Ellen Molteberg, Per M Thorsby, Magnhild Kverneland, Per Ole Iversen, Kaja K Selmer, Dag Hofoss, Karl O Nakken, Erik Taubøll   +7 more
doaj   +1 more source

Correlation between the size of pheochromocytoma and the level of metanephrines

Endocrine Regulations, 2023
Objective. Pheochromocytomas (PHEO) and paraganglioma (PGLs) are rare neuroendocrine catecholamine-producing tumors that arise from the chromaffin cells of either the adrenal medulla or extra-adrenal paraganglionic tissues. Despite the recent advances in
Rezkallah Emad, Elsaify Andrew, Hanna Ragai, Elsaify Wael   +3 more
doaj   +1 more source

A Laboratory Medicine Perspective on the Investigation of Phaeochromocytoma and Paraganglioma

Diagnostics, 2023
Phaeochromocytomas (PC) and sympathetic paragangliomas (PGL) are potentially malignant tumours arising from the adrenal medulla (PC) or elsewhere in the sympathetic nervous system (PGL).
Christopher S. Boot
doaj   +1 more source

Hypermetabolism and Substrate Utilization Rates in Pheochromocytoma and Functional Paraganglioma

Biomedicines, 2022
The overproduction of catecholamines in pheochromocytoma/paraganglioma (PPGL) induces a hypermetabolic state. The aim of this study was to evaluate the incidence of a hypermetabolic state and differences in substrate metabolism in consecutive PPGL ...
Ondřej Petrák, Denisa Haluzíková, Judita Klímová, Matěj Zítek, Robert Holaj, David Michalský, Květoslav Novák, Radka Petráková-Doležalová, Jan Kvasnička, Thi Minh Phuong Nikrýnová Nguyen, Zuzana Krátká, Martin Matoulek, Jiří Widimský, Tomáš Zelinka   +13 more
doaj   +1 more source

Phasing-in plasma metanephrines determination [PDF]

European Journal of Endocrinology, 2013
ObjectivesWe set up plasma normetanephrine (pNMA) and metanephrine (pMA) assays as they demonstrated their usefulness for diagnosing phaeochromocytomas. Our scope is to describe some practical laboratory aspects and the clinical relevance of these assays in our endocrinological or cardiological departments.MethodsWe retrospectively reviewed the results
Brossaud, Julie, Gosse, Philippe, Gatta, Blandine, Tabarin, Antoine, Simonnet, Guy, Corcuff, Jean-Benoît   +5 more
openaire   +4 more sources