Results 181 to 190 of about 85,166 (274)

First karyotype description of the Indochinese shrew <i>Crocidura indochinensis</i> Robinson et Kloss, 1922 (Mammalia, Eulipotyphla, Soricidae) from Yunnan, China. [PDF]

Comp Cytogenet
Jin J, Dai J, Ye J.
europepmc   +1 more source

Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats

Aging Cell, Volume 25, Issue 9, September 2026.
Using genetically heterogeneous rats carrying divergent mitochondrial haplotypes on a randomized nuclear background, we show that mtDNA variation modifies the rate of ovarian aging. OKC‐HETW ovaries showed bioenergetic deficits, reduced mtDNA copy number, and impaired TFAM–mtDNA binding by 4 months of age, with early fibrosis and immune infiltration ...
Subhasri Biswas, Hoang V. M. Nguyen, Aubrey Converse, Satoshi Matsuzaki, Michael T. Kinter, Kenneth M. Humphries, Willard M. Freeman, Sarah R. Ocañas, Arlan Richardson, Francesca E. Duncan, Tommy L. Lewis Jr, Michael B. Stout   +11 more
wiley   +1 more source

Molecular divergence and genomic composition of B chromosomes in the fish Cyphocharax modestus (Characiformes, Curimatidae). [PDF]

Sci Rep
Dos Santos N, Sassi FMC, Dos Santos RZ, Goes CAG, de Moraes RLR, Porto-Foresti F, Liehr T, Cioffi MB, Utsunomia R.   +8 more
europepmc   +1 more source

Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development

Cancer Science, Volume 117, Issue 9, Page 2335-2344, September 2026.
Dysregulated cell cycle control often involves alternative compensatory pathways in cancers to maintain its robustness but provide unique targetable vulnerabilities. We overview recent insights on cancer‐specific vulnerabilities across the cell cycle and discuss how these can be used to develop new therapeutic strategies.
Nana Kamakura, Minji Jo, Motoko Takahashi, Toru Hirota   +3 more
wiley   +1 more source

ZNF512B associates with mitotic spindles, regulates metaphase exit, and is crucial for stem cell differentiation. [PDF]

Nucleic Acids Res
Paasche LW, Daus N, Groos JJ, Diegmüller F, Kreienbaum C, Kobakhidze E, Lan J, Leers J, Wunderlich S, Scheibe M, Butter F, Borchers A, Mackay JP, Wunderlich TM, Hake SB.   +14 more
europepmc   +1 more source

Deciphering the Dysregulated Pathways and Candidate Therapeutic Compounds for Primary Ovarian Cancer Using Whole Transcriptomics Data and Next Generation Knowledge Discovery Strategies

Journal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Ovarian cancer (OC) is a type of gynaecological cancer with a higher mortality rate due to diagnosis at an advanced stage and limited treatment options. This study aimed to leverage transcriptomic data to identify cellular and molecular pathways and potential anti‐cancer compounds that specifically target primary invasive epithelial ovarian ...
Peter Natesan Pushparaj, Kalamegam Gauthaman, Alaa G. Alahmadi, Reem Nabil Hassan, Hind A. Alkhatabi, Ammar AL‐Farga   +5 more
wiley   +1 more source

The centriculum, a membrane reticulum that surrounds Caenorhabditis elegans centrosomes, might serve as a microtubule filter. [PDF]

J Cell Sci
Maheshwari R, Rahman MM, Ruddick A, Drey S, Mirabello RS, Cohen-Fix O.   +5 more
europepmc   +1 more source

Dynamic evolution and hierarchical regulation of rDNA in polyploid oat

The Plant Journal, Volume 127, Issue 6, September 2026.
SUMMARY Ribosomal DNA (rDNA) encodes the RNA core of ribosomes, yet it remains one of the least understood components of eukaryotic genomes, particularly in complex polyploids. Here, we present a comprehensive analysis of rDNA organization, evolution, and transcription across the Avena genus. We show that rDNA copy number varies extensively across loci
Ziyang Wan, Haorang Wang, Jie Qin, Wentao Ding, Xin Wang, Qianqian Ge, Handong Su   +6 more
wiley   +1 more source

SCP4 dephosphorylates mitotic histone H3 to maintain chromosome stability. [PDF]

EMBO Rep
Zheng Y, Zhang Z, Wang Q, Cao J, Li Y, Liang T, Feng XH, Lin X.   +7 more
europepmc   +1 more source

The Secret (Mitotic) Life of Clathrin

Traffic, Volume 27, Issue 3, September 2026.
A perspective on the function of clathrin at the mitotic spindle during cell division. ABSTRACT The discovery of clathrin was a foundational event in membrane traffic research. Its identification as the major protein component of the coat that surrounds endocytic vesicles kickstarted the biochemical and molecular characterization of endocytosis. During
Stephen J. Royle
wiley   +1 more source