Results 51 to 60 of about 40,289 (207)

TFF3 initiates gastric intestinal metaplasia by activating JAK2 and STAT3 under high salt conditions

Scientific Reports
The mechanism underlying the role of trefoil factor family 3 (TFF3) in intestinal metaplasia remains unclear. This study reveals the molecular mechanism by which TFF3, in the process of gastric mucosal epithelial cell intestinal metaplasia (IM) induced ...
Yanhong Wang, Feifei Qian, Baodong Shan, Li Zhang, Jie Zhong, Song Chen, Manman Yao, Shengnan Li, Xixiang Cao, Sujuan Fei, Xunlei Pang   +10 more
doaj   +1 more source

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation [PDF]

, 2013
A role for WNT signalling in gastric carcinogenesis has been suggested due to two major observations. First, patients with germline mutations in adenomatous polyposis coli (APC) are susceptible to stomach polyps and second, in gastric cancer, WNT ...
A Gregorieff, A Horii, A Jung, A Novak, AC de Vries, AN Milne, AT Franco, B Kim, B Tycko, C Cavard, D Athineos, D M Pritchard, DM Parkin, E Half, E Tahara, EF Chan, G Gatta, H Guillen-Ahlers, H Ireland, H Luche, H Nagase, H Oshima, H Shibata, H Watanabe, H Zhang, HC Zheng, HJ Freeman, J Cordero, J Neumann, J Parsonnet, J Woodgett, JG Forte, K Miyazawa, K Oien, KF Becker, KW Kinzler, LK Bianchi, M Crabtree, M Iida, M Nakayama, M Shitashige, M Suzuki, M Suzuki, M Torbenson, MG Smith, MP Ebert, N Barker, N Barker, N Barker, N Barker, N Barker, N Harada, N Murata-Kamiya, N Uemura, O J Sansom, O Sokolova, O Tetsu, OJ Sansom, P Blache, P Correa, P Correa, P Lauren, P Salgueiro, P Soriano, PJ Guilford, R A Ridgway, R Kemp, R Poulsom, S Garrean, S Nakatsuru, S Patel, S Patel, S Radulescu, S Segditsas, S Sekine, SC Abraham, SC Abraham, SM Przemeck, SS Ng, T Gnad, T Oda, TC He, WM Clements, WS Park, XC He, Y Miyoshi, Y Park do, Z Spicer, Z Zhao   +88 more
core   +1 more source

Anatomical predilection of intestinal metaplasia based on 78,335 endoscopic cases

The Saudi Journal of Gastroenterology, 2016
Background/Aims: Gastric intestinal metaplasia (IM) is an important risk factor for intestinal-type gastric carcinoma, and successful treatment critically depends on its timely detection.
Xin-Yi Mao, Shun-Fu Xu, Qing Liu, Jian-Xia Jiang, Hai-Han Zhang, Huai-Ming Sang, Guo-Xin Zhang   +6 more
doaj   +1 more source

切除胃全割切片によるHelicobacter pyloriと化生性病変の分布についての免疫組織化学的研究 [PDF]

, 2001
　Chronic active gastritis caused by Helicobacter pylori (H pylori) infection tends to progress to atrophic gastritis and is often associated with intestinal metaplasia of the foveolar epithelia and pseudopyloric gland metaplasia in the fundic gland area.
伴 慎一, 金 仁順, 高濱 素秀
core  

Prevalence of High-Risk Groups for Gastric Carcinoma – A Biopsy Finding

Nepalese Medical Journal, 2018
Introduction: Gastric carcinoma is leading cause of death world wide including Nepal. The 5 years survival rate of gastric carcinoma (25%) has drastically decreased compared to early gastric cancers (90-90%) hence implying the need for early detection ...
Geetika KC, Shiva Raj KC, Purnima Gyawali   +2 more
doaj   +1 more source

Polypoidal Intestinal Metaplasia and Dysplasia of the External Urethral Meatus

Case Reports in Nephrology, 2012
Urethral mucosa with intestinal metaplasia and dysplasia is a rare occurrence. To date only a single case has been reported in a male with long-standing urethral stricture. We present a 33-year-old female with polypoid intestinal metaplasia and dysplasia
Mary Mathew, Bhavna Nayal, Lakshmi Rao, Raghunath Narayanan Unni, Joseph Thomas   +4 more
doaj   +1 more source

Role of transcription factor Cdx2 in the development of gastric intestinal metaplasia

Patologìâ, 2012
The role of intestinal differentiation transcription factor Cdx2 in the development of gastric intestinal metaplasia was established on the basis of its expression in material of gastric mucosa biopsies.
S. V. Vernygorodskiy, L. V. Degtyaryova
doaj   +1 more source

Murine Models of Gastric Corpus PreneoplasiaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of
Christine P. Petersen, Jason C. Mills, James R. Goldenring   +2 more
doaj   +1 more source

Reproducibilidad del diagnóstico histopatológico de lesiones precursoras del carcinoma gástrico en tres países latinoamericanos [PDF]

, 2010
Objetivo. Evaluar la concordancia en el diagnóstico de lesiones precursoras del carcinoma gástrico de tipo intestinal entre observadores con diferente experiencia. Material y métodos.
Aguirre-García, Jesús, Bravo, Luis Eduardo, Bravo-Rodríguez, Juan Carlos, Flores-Luna, Lourdes, Hernández-Suárez, Gustavo, Kasamatsu, Elena, Nunes-Velloso, María del Carmen   +6 more
core   +1 more source

Amphiregulin-Deficient Mice Develop Spasmolytic Polypeptide Expressing Metaplasia and Intestinal Metaplasia [PDF]

Gastroenterology, 2009
The loss of parietal cells from the fundic mucosa leads to the emergence of metaplastic lineages associated with an increased susceptibility to neoplastic transformation. Both intestinal metaplasia (IM) and spasmolytic polypeptide (TFF2/SP) expressing metaplasia (SPEM) have been identified in human stomach, but only SPEM is present in most mouse models
Ki Taek, Nam, Hyuk-Joon, Lee, Hoyin, Mok, Judith, Romero-Gallo, James E, Crowe, Richard M, Peek, James R, Goldenring   +6 more
openaire   +3 more sources