Results 131 to 140 of about 18,825 (316)

Convergent Neuronal Plasticity and Metaplasticity Mechanisms of Stress, Nicotine, and Alcohol.

open access: yesAnnual Review of Pharmacology and Toxicology, 2018
Stress and tobacco smoking are risk factors for alcoholism, but the underlying neural mechanisms are not well understood. Although stress, nicotine, and alcohol have broad, individual effects in the brain, some of their actions converge onto the same ...
A. Ostroumov, J. Dani
semanticscholar   +1 more source

Mechanisms of Homeostatic Synaptic Plasticity in vivo

open access: yesFrontiers in Cellular Neuroscience, 2019
Synapses undergo rapid activity-dependent plasticity to store information, which when left uncompensated can lead to destabilization of neural function.
Hey-Kyoung Lee   +2 more
doaj   +1 more source

Data mining for the diagnosis of type 2 diabetes [PDF]

open access: yes, 2012
Diabetes is the most common disease nowadays in all populations and in all age groups. diabetes contributing to heart disease, increases the risks of developing kidney disease, blindness, nerve damage, and blood vessel damage.
Andina de la Fuente, Diego   +1 more
core  

Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus [PDF]

open access: yes, 1997
Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the ...
Harris, Kristen M.   +4 more
core   +2 more sources

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

open access: yesNeurogastroenterology &Motility, EarlyView.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech   +4 more
wiley   +1 more source

A unifying theory of synaptic long-term plasticity based on a sparse distribution of synaptic strength

open access: yesFrontiers in Synaptic Neuroscience, 2014
Long-term synaptic plasticity is fundamental to learning and network function. It has been studied under various induction protocols and depends on firing rates, membrane voltage, and precise timing of action potentials.These protocols show different ...
Daniel eKrieg, Jochen eTriesch
doaj   +1 more source

A Neural Network Approach for Analyzing the Illusion of Movement in Static Images

open access: yes, 2008
The purpose of this work is to analyze the illusion of movement that appears when seeing certain static images. This analysis is accomplished by using a biologically plausible neural network that learned (in a unsupervised manner) to identify the ...
Andina de la Fuente, Diego   +3 more
core  

Proposal for a New Classification of Rare Cancers Adopting Updated Histological Tumor Types

open access: yesPathology International, EarlyView.
We propose a new rare cancer classification system using the updated International Classification of Diseases for Oncology 3.2 coding system and the World Health Organization Classification of Tumors 5th edition. This list could serve as a diagnostic classifier to reliably distinguish various rare cancers for clinical applications.
Ryoko Rikitake   +8 more
wiley   +1 more source

Preconditioning tDCS facilitates subsequent tDCS effect on skill acquisition in older adults. [PDF]

open access: yes, 2017
Functional motor declines that often occur with advancing age-including reduced efficacy to learn new skills-can have a substantial impact on the quality of life.
Amadi   +88 more
core   +1 more source

Diversity of Astroglial Effects on Aging- and Experience-Related Cortical Metaplasticity

open access: yesFrontiers in Molecular Neuroscience, 2018
Activity-dependent regulation of synaptic plasticity, or metaplasticity, plays a key role in the adaptation of neuronal networks to physiological and biochemical changes in aging brain.
U. Lalo   +2 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy