Neurogranin Regulates Metaplasticity [PDF]
Frontiers in Molecular Neuroscience, 2020 Long-term potentiation (LTP) and long-term depression (LTD) are two major forms of synaptic plasticity that are widely accepted as cellular mechanisms involved in learning and memory.
Ling Zhong, Nashaat Z. Gerges
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Synaptic Variability Introduces State-Dependent Modulation of Excitatory Spinal Cord Synapses [PDF]
Neural Plasticity, 2015 The relevance of neuronal and synaptic variability remains unclear. Cellular and synaptic plasticity and neuromodulation are also variable. This could reflect state-dependent effects caused by the variable initial cellular or synaptic properties or ...
David Parker
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Effects of TrkB-related induced metaplasticity within the BLA on anxiety, extinction learning, and plasticity in BLA-modulated brain regions [PDF]
Behavioral and Brain FunctionsBackground Neuronal plasticity within the basolateral amygdala (BLA) is fundamental for fear learning. Metaplasticity, the regulation of plasticity states, has emerged as a key mechanism mediating the subsequent impact of emotional and stressful ...
Joyeeta Dutta Hazra +10 more
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Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats [PDF]
Frontiers in Molecular Neuroscience, 2014 The second messenger cyclic GMP affects synaptic transmission and modulates synaptic plasticity and certain types of learning and memory processes. The impact of the natriuretic peptide receptor B (NPR-B) and its ligand C-type natriuretic peptide (CNP ...
Gleb eBarmashenko +6 more
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Probabilistic metaplasticity for continual learning with memristors in spiking networks [PDF]
Scientific ReportsEdge devices operating in dynamic environments critically need the ability to continually learn without catastrophic forgetting. The strict resource constraints in these devices pose a major challenge to achieve this, as continual learning entails memory
Fatima Tuz Zohora +3 more
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Promoting neurological recovery of function via metaplasticity [PDF]
, 2010 The modification of synapses by neural activity has been proposed to be the substrate for experience-dependent brain development, learning, and recovery of visual function after brain injury.
Abraham +39 more
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Metaplastic Breast Cancer [PDF]
Mayo Clinic Proceedings, 2021 Beiyun, Chen, Lori A, Erickson
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Systemic pharmacological suppression of neural activity reverses learning impairment in a mouse model of Fragile X syndrome [PDF]
eLifeThe enhancement of associative synaptic plasticity often results in impaired rather than enhanced learning. Previously, we proposed that such learning impairments can result from saturation of the plasticity mechanism (Nguyen-Vu et al., 2017), or, more ...
Amin MD Shakhawat +4 more
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Neuroscience, 2021 descripción no proporcionada por ...
Trejo, José L., Sotiropoulos, Ioannis
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Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1
Scientific Reports, 2022 Long-term potentiation (LTP) is regulated in part by metaplasticity, the activity-dependent alterations in neural state that coordinate the direction, amplitude, and persistence of future synaptic plasticity.
Anurag Singh +3 more
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