Results 11 to 20 of about 15,121 (239)

Synaptic metaplasticity in binarized neural networks [PDF]

open access: yesComputational and Systems Neuroscience (Cosyne) 2021, 2020
While deep neural networks have surpassed human performance in multiple situations, they are prone to catastrophic forgetting: upon training a new task, they rapidly forget previously learned ones.
Axel Laborieux   +3 more
semanticscholar   +3 more sources

Editorial: Non-invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders

open access: yesFrontiers in Neurology, 2021
Department of Neurology, Sant’Elia Hospital, ASP Caltanissetta, Caltanissetta, Italy, Department of Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy, Department of Neurology IC, Oasi Research Institute–IRCCS, Troina, Italy,
Mariagiovanna Cantone   +4 more
semanticscholar   +1 more source

Concordance of breast cancer biomarker testing in core needle biopsy and surgical specimens: A single institution experience

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4954-4965, December 2022., 2022
Retesting estrogen receptor and HER2 status provides more clinical benefit than retesting progesterone receptor status. We propose guidelines for retesting receptor profiles to aid patient care management decisions, prioritize clinical benefits, and minimize healthcare costs.
Jessica A. Slostad   +5 more
wiley   +1 more source

The Complex Formed by Group I Metabotropic Glutamate Receptor (mGluR) and Homer1a Plays a Central Role in Metaplasticity and Homeostatic Synaptic Scaling

open access: yesJournal of Neuroscience, 2021
G-protein-coupled receptors can be constitutively activated following physical interaction with intracellular proteins. The first example described was the constitutive activation of Group I metabotropic glutamate receptors (mGluR: mGluR1,5) following ...
J. Bockaert, J. Perroy, F. Ango
semanticscholar   +1 more source

Naturalistic Spike Trains Drive State-Dependent Homeostatic Plasticity in Superficial Layers of Visual Cortex

open access: yesFrontiers in Synaptic Neuroscience, 2021
The history of neural activity determines the synaptic plasticity mechanisms employed in the brain. Previous studies report a rapid reduction in the strength of excitatory synapses onto layer 2/3 (L2/3) pyramidal neurons of the primary visual cortex (V1)
Varun Chokshi   +13 more
doaj   +1 more source

Dynamic Interplay between Lower-Grade Glioma Instability and Brain Metaplasticity: Proposal of an Original Model to Guide the Therapeutic Strategy

open access: yesCancers, 2021
Simple Summary The behavior of diffuse lower-grade glioma (LGG) is changing over time, spontaneously, and in reaction to therapies. Due to genomic instability and clonal expansion, although LGG initially progresses slowly, the growth accelerates at the ...
H. Duffau
semanticscholar   +1 more source

Osteohistological characterization of notosuchian osteoderms: Evidence for an overlying thick leathery layer of skin

open access: yesJournal of Morphology, Volume 284, Issue 1, January 2023., 2023
The perpendicular insertion of Sharpey's fibers in the external cortex suggests the presence of a thick leathery skin layer overlying notosuchian osteoderms. Although intramembranous ossification is the main process involved in the development of crocodyliform osteoderms, we reported a case of metaplastic development.
Mariana Valéria de Araújo Sena   +12 more
wiley   +1 more source

Further evidence that CP-AMPARs are critically involved in synaptic tag and capture at hippocampal CA1 synapses

open access: yesMolecular Brain, 2021
The synaptic tag and capture (STC) hypothesis provides an important theoretical basis for understanding the synaptic basis of associative learning. We recently provided pharmacological evidence that calcium-permeable AMPA receptors (CP-AMPARs) are a ...
Pojeong Park   +5 more
doaj   +1 more source

Prognostic factors and genetic markers in thymic epithelial tumors: A narrative review

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3242-3249, December 2022., 2022
The aim of this review article is to discuss the different prognostic factors and genetic markers of TET and to point out discrepancies and similarities among the available literature (concerning prognostic factors) and more importantly to demonstrate the genetic pathways that could be the basis of a development of new targeted therapies.
Apostolos C. Agrafiotis   +5 more
wiley   +1 more source

Carrier-capture-assisted optoelectronics based on van der Waals materials to imitate medicine-acting metaplasticity

open access: yesnpj 2D Materials and Applications, 2021
Recently, researchers have focused on optoelectronics based on two-dimensional van der Waals materials to realize multifunctional memory and neuron applications. Layered indium selenide (InSe) semiconductors satisfy various requirements as photosensitive
Qianfan Nie   +13 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy