Results 21 to 30 of about 9,066 (204)

Ethanol enhances neurosteroidogenesis in hippocampal pyramidal neurons by paradoxical NMDA receptor activation [PDF]

, 2011
Using an antibody against 5α-reduced neurosteroids, predominantly allopregnanolone, we found that immunostaining in the CA1 region of rat hippocampal slices was confined to pyramidal neurons.
Izumi, Yukitoshi, Tokuda, Kazuhiro, Zorumski, Charles F   +2 more
core   +2 more sources

Cathodal Occipital tDCS is unable to modulate The Sound Induced Flash Illusion in migraine [PDF]

, 2019
Migraine is a highly disabling disease characterized by recurrent pain.Despite an intensive effort, mechanisms of migraine pathophysiology, still represent an unsolved issue.
Filippo Brighina, Giuseppe Cosentino, Giuseppe Giglia, GIUSEPPE SALEMI, Massimo Gangitano, Nadia Bolognini, Simona Maccora   +6 more
core   +1 more source

On the Biological Plausibility of Artificial Metaplasticity [PDF]

, 2011
The training algorithm studied in this paper is inspired by the biological metaplasticity property of neurons. Tested on different multidisciplinary applications, it achieves a more efficient training and improves Artificial Neural Network Performance ...
A. Artola, A. Marcano-Cedeño, B. Mockett, C.E. Shannon, D. Bolle, D.W. Rucky, E. Kinto, E. Long De, E.L. Bienestock, G. Daoudal, G. Neves, J. Egan, J. Ropero-Pelaez, M. Chiappalone, R.H. Cudmore, T.J. Sejnowski, T.J. Sejnowski, W.C. Abraham, W.C. Abraham, W.C. Abraham, W.C. Abraham   +20 more
core   +1 more source

Transcranial magnetic stimulation provides means to assess cortical plasticity and excitability in humans with fragile X syndrome and autism spectrum disorder

Frontiers in Synaptic Neuroscience, 2010
Fragile X Syndrome (FXS) is the most common heritable cause of intellectual disability. In vitro electrophysiologic data from mouse models of FXS suggest that loss of Fragile X Mental Retardation Protein (FMRP) affects intracortical excitability and ...
Lindsay M Oberman, Frederick Ifert-Miller, Umer Najib, Shahid Bashir, Ione Woollacott, Joseph Gonzalez-Heydrich, Jonathan Picker, Jonathan Picker, Alexander Rotenberg, Alexander Rotenberg, Alvaro Pascual-Leone   +10 more
doaj   +1 more source

Probabilistic versus incremental presynaptic learning in biological plausible synapses [PDF]

, 2011
In this paper, the presynaptic rule, a classical rule for hebbian learning, is revisited. It is shown that the presynaptic rule exhibits relevant synaptic properties like synaptic directionality, and LTP metaplasticity (long-term potentiation threshold ...
Andina de la Fuente, Diego, Ropero Peláez, Javier   +1 more
core   +2 more sources

Plasticity in the Prefrontal Cortex of Adult Rats

Frontiers in Cellular Neuroscience, 2015
We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social experience, metaplastic experiences,
Bryan eKolb, Robbin eGibb
doaj   +1 more source

A Prediction Model to Diabetes using Artificial Metaplasticity [PDF]

, 2011
Diabetes is the most common disease nowadays in all populations and in all age groups. Different techniques of artificial intelligence has been applied to diabetes problem.
C.E. Shannon, E.I. Mohamed, H. Leung, H. Temurtas, J.E. Shaw, K. Polat, K. Polat, M.T. Hagan, W.C. Abraham   +8 more
core   +1 more source

Promoting neurological recovery of function via metaplasticity [PDF]

, 2010
The modification of synapses by neural activity has been proposed to be the substrate for experience-dependent brain development, learning, and recovery of visual function after brain injury.
Abraham, Abraham, Barria, Bear, Bienenstock, Blais, Chen, Cho, Clothiaux, Gardoni, Hamada, Iezzi, Kathleen KA Cho, Kirkwood, Kirkwood, Kuo, Laurie, Mark F Bear, Mioche, Perez-Otano, Philpot, Philpot, Philpot, Priestley, Quinlan, Quinlan, Sans, Sato, Sheng, Smith, Sobczyk, Steigerwald, Thickbroom, Todd, Vicini, Vissel, Watanabe, Wiesel, Xu, Yoshii   +39 more
core   +1 more source

The computational power of astrocyte mediated synaptic plasticity

Frontiers in Computational Neuroscience, 2012
Research in the last two decades has made clear that astrocytes play a crucial role in the brain beyond their functions in energy metabolism and homeostasis.
Rogier eMin, Mirko eSantello, Thomas eNevian   +2 more
doaj   +1 more source

Use of a metaplasticity-based protocol of therapeutic transcranial magnetic stimulation in patients with progressive multiple sclerosis and spasticity: first experience

Нервно-мышечные болезни, 2022
Background. Spasticity is a disabling syndrome frequently observed in progressive multiple sclerosis. One of the promising approaches to the treatment of spasticity is the use of therapeutic intermittent theta‑burst transcranial magnetic stimulation.
I. S. Bakulin, A. G. Poydasheva, A. H. Zabirova, D. Yu. Lagoda, A. A. Rimkevichus, M. N. Zakharova, N. A. Suponeva, M. A. Piradov   +7 more
doaj   +1 more source