Results 41 to 50 of about 15,121 (239)

The computational power of astrocyte mediated synaptic plasticity

Frontiers in Computational Neuroscience, 2012
Research in the last two decades has made clear that astrocytes play a crucial role in the brain beyond their functions in energy metabolism and homeostasis.
Rogier eMin, Mirko eSantello, Thomas eNevian   +2 more
doaj   +1 more source

Correction of amblyopia in cats and mice after the critical period

eLife, 2021
Monocular deprivation early in development causes amblyopia, a severe visual impairment. Prognosis is poor if therapy is initiated after an early critical period.
Ming-fai Fong, Kevin R Duffy, Madison P Leet, Christian T Candler, Mark F Bear   +4 more
doaj   +1 more source

Power-law forgetting in synapses with metaplasticity [PDF]

J. Stat. Mech. (2011) P09025, 2011
The idea of using metaplastic synapses to incorporate the separate storage of long- and short-term memories via an array of hidden states was put forward in the cascade model of Fusi et al. In this paper, we devise and investigate two models of a metaplastic synapse based on these general principles.
arxiv   +1 more source

Multiple forms of metaplasticity at a single hippocampal synapse during late postnatal development

Developmental Cognitive Neuroscience, 2015
Metaplasticity refers to adjustment in the requirements for induction of synaptic plasticity based on the prior history of activity. Numerous forms of developmental metaplasticity are observed at Schaffer collateral synapses in the rat hippocampus at the
Daniel G. McHail, Theodore C. Dumas
doaj   +1 more source

Stress-Induced Enhanced Long-Term Potentiation and Reduced Threshold for N-Methyl-D-Aspartate Receptor- and β-Adrenergic Receptor-Mediated Synaptic Plasticity in Rodent Ventral Subiculum

Frontiers in Molecular Neuroscience, 2021
Stress is a biologically relevant signal and can modulate hippocampal synaptic plasticity. The subiculum is the major output station of the hippocampus and serves as a critical hub in the stress response network.
Julia C. Bartsch, Monique von Cramon, Monique von Cramon, David Gruber, Uwe Heinemann, Joachim Behr, Joachim Behr, Joachim Behr   +7 more
doaj   +1 more source

Synaptic plasticity and preliminary-spike-enhanced plasticity in a CMOS-compatible Ta2O5 memristor

Materials & Design, 2020
An artificial synapse that can perform both learning and memory functions was realized using an amorphous Ta2O5 memristor. A Pt/Ta2O5/TiN memristor, with an amorphous Ta2O5 film grown at 100 °C, exhibited reliable bipolar switching properties at the ...
Hyun–Gyu Hwang, Jong–Un Woo, Tae–Ho Lee, Sung-Mean Park, Tae–Gon Lee, Woong-Hee Lee, Sahn Nahm   +6 more
doaj  

Transcranial magnetic stimulation reveals diminished homoeostatic metaplasticity in cognitively impaired adults

Brain Communications, 2020
Homoeostatic metaplasticity is a neuroprotective physiological feature that counterbalances Hebbian forms of plasticity to prevent network destabilization and hyperexcitability.
M. Sundman, K. Lim, Viet Ton That, J. Mizell, C. Ugonna, Rudolph Rodriguez, N. Chen, A. Fuglevand, Yilin Liu, Robert C. Wilson, J. Fellous, S. Rapcsak, Y. Chou   +12 more
semanticscholar   +1 more source

Preconditioning human pharyngeal motor cortex enhances directional metaplasticity induced by repetitive transcranial magnetic stimulation

Journal of Physiology, 2020
Recent studies have proposed therapeutic potential for repetitive transcranial magnetic stimulation (rTMS) in swallowing rehabilitation, yet its outcomes vary across individuals and studies.
Ivy Cheng, Honor Scarlett, Mengqing Zhang, S. Hamdy   +3 more
semanticscholar   +1 more source

Synaptic Variability Introduces State-Dependent Modulation of Excitatory Spinal Cord Synapses

Neural Plasticity, 2015
The relevance of neuronal and synaptic variability remains unclear. Cellular and synaptic plasticity and neuromodulation are also variable. This could reflect state-dependent effects caused by the variable initial cellular or synaptic properties or ...
David Parker
doaj   +1 more source

Unraveling the cellular and molecular mechanisms of repetitive magnetic stimulation

Frontiers in Molecular Neuroscience, 2013
Despite numerous clinical studies, which have investigated the therapeutic potential of repetitive transcranial magnetic stimulation (rTMS) in various brain diseases, our knowledge of the cellular and molecular mechanisms underlying rTMS-based therapies ...
Florian eMüller-Dahlhaus, Andreas eVlachos   +1 more
doaj   +1 more source