Results 41 to 50 of about 9,066 (204)

Regulation of Neuromodulator Receptor Efficacy - Implications for Whole-Neuron and Synaptic Plasticity [PDF]

, 2004
Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy - a phenomenon which influences the individual cell's response to central signals of NM release.
Scheler, Gabriele
core   +1 more source

Controllable Charge Storability in InP/ZnSe Core/Shell Quantum Dots toward Bioinspired Optical Synaptic Application

Advanced Science, EarlyView.
A field‐effect transistor incorporating type‐I InP/ZnSe core–shell quantum dots demonstrates light‐ and gate‐tunable synaptic plasticity. By leveraging field‐assisted photoinduced charge trapping, the device emulates essential neuromorphic functions, including paired‐pulse facilitation, memory consolidation, and classical conditioning.
Guohao Wen, Bingbing Huo, Dingting Zheng, Xiang Zheng, Guanlin Ke, Zhiguo Chi, Honglei Wu, Botao Ji, Zhenhua Sun   +8 more
wiley   +1 more source

Emerging Link between Alzheimer’s Disease and Homeostatic Synaptic Plasticity

Neural Plasticity, 2016
Alzheimer’s disease (AD) is an irreversible brain disorder characterized by progressive cognitive decline and neurodegeneration of brain regions that are crucial for learning and memory.
Sung-Soo Jang, Hee Jung Chung
doaj   +1 more source

Intra- and Inter-Regional Priming of Ipsilateral Human Primary Motor Cortex With Continuous Theta Burst Stimulation Does Not Induce Consistent Neuroplastic Effects

Frontiers in Human Neuroscience, 2018
Human responses to non-invasive brain stimulation (NIBS) techniques can be highly variable. Recently, priming protocols involving a conditioning round of NIBS applied to a target brain region prior to the application of a test protocol have shown promise
Michael Do, Melissa Kirkovski, Charlotte B. Davies, Soukayna Bekkali, Linda K. Byrne, Peter G. Enticott   +5 more
doaj   +1 more source

GluN2D NMDA Receptors Gate Fear Extinction Learning and Interneuron Plasticity

Frontiers in Synaptic Neuroscience, 2021
The cerebellum is critically involved in the formation of associative fear memory and in subsequent extinction learning. Fear conditioning is associated with a long-term potentiation at both excitatory and inhibitory synapses onto Purkinje cells.
Christophe J. Dubois, Siqiong June Liu, Siqiong June Liu   +2 more
doaj   +1 more source

Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus [PDF]

, 1997
Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the ...
Harris, Kristen M., Kantor, David, Kennedy, Mary B., Ouyang, Yannan, Schuman, Erin M.   +4 more
core   +2 more sources

Simultaneous Dual‐Plasticity Organic Synaptic Transistor for Neuromorphic Computing

Advanced Electronic Materials, EarlyView.
This study presents a DNTT‐based organic field‐effect transistor that demonstrates synaptic plasticity under optical stimulation. The device simultaneously implements both short‐term and long‐term plasticity mechanisms, enabling simultaneous working memory and persistent information storage functions, with enhancement exceeding 10 000%.
Tomas Vincze, Michal Hanic, Martin Berki, Martin Weis   +3 more
wiley   +1 more source

Neural mechanisms of social learning in the female mouse [PDF]

, 2017
Social interactions are often powerful drivers of learning. In female mice, mating creates a long-lasting sensory memory for the pheromones of the stud male that alters neuroendocrine responses to his chemosignals for many weeks.
Abraham, Abraham, Arnson, Bakker, Barkai, Barth, Ben-Shaul, Brennan, Brennan, Brennan, Brennan, Brennan, Brennan, Bruce, Burns-Cusato, Caligioni, Castro, Chamero, Clancy, Daoudal, Desai, Dietz, Dulac, Dulac, Fan, Guenthner, Halem, Harvey, Hendrickson, Hull, Hurst, Ichikawa, Isaacson, Kaba, Kaba, Kendrick, Keverne, Kimchi, Lee, Li, Lin, Luo, Lévy, Mak, Margrie, Matsuoka, Matsuoka, Matsuoka, Meeks, Mozzachiodi, Nolan, Nolan, Preston, Reijmers, Reijmers, Ross, Rosser, Sakurai, Shepherd, Shingo, Shpak, Shpak, Stackman, Stowers, Ström, Tachikawa, Takahashi, Tirindelli, Tolokh, Turrigiano, Wallace, Wang, Wang, Wang, Wu, Yassin, Yiu, Young, Zhang, Zhou   +79 more
core   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

Clinical Anatomy, EarlyView.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico, Tanaz Saatchi, Silvia Urbani, Vanni Rizzatti, Gloria Mazzali, Francesco Fantin, Silvia Faccioli, Alessandro Gavras, Mauro Zamboni, Anna Giani   +9 more
wiley   +1 more source