Synaptic lability after experience-dependent plasticity is not mediated by calcium-permeable AMPARs
Activity- or experience-dependent plasticity has been associated with the trafficking of calcium-permeable AMPARs (CP-AMPARs) in a number of experimental systems.
Jing A Wen, Alison L Barth
doaj +1 more source
Excitability of the motor cortex in patients with migraine changes with the time elapsed from the last attack [PDF]
BACKGROUND: Motor-evoked potentials (MEPs) produced by single-pulse transcranial magnetic stimulation (TMS) of the motor cortex can be an objective measure of cortical excitability.
COPPOLA, GIANLUCA +6 more
core +1 more source
Abstract Artificial intelligence technology has spread rapidly in the business world in recent years and has transformed the business processes of many organizations. This transformation has caused significant changes not only in the technological infrastructure but also in the organizational culture and way of doing business.
Aslıhan Canbul Yaroğlu
wiley +1 more source
Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang +13 more
wiley +1 more source
Is neural hyperpolarization by cathodal stimulation always detrimental at the behavioral level?
Cathodal transcranial direct current stimulation (c-tDCS) is usually considered an inhibitory stimulation. From a physiological perspective, c-tDCS stimulation induces hyperpolarization at the neural level.
Cornelia ePirulli +3 more
doaj +1 more source
Metaplastic LTP inhibition after LTD induction in CA1 hippocampal slices involves NMDA receptor‐mediated neurosteroidogenesis [PDF]
Long-term depression (LTD) induced by low-frequency electrical stimulation (LFS) in the CA1 region of the hippocampus is a form of synaptic plasticity thought to contribute to learning and memory and to the pathophysiology of neuropsychiatric disorders ...
Izumi, Yukitoshi +2 more
core +2 more sources
Co‐expression of high TGF‐β1 and PD‐L1 was linked to the poorest prognosis (5‐year FFR: 46.1%) and was identified as an independent predictor of recurrence (adjusted hazard ratio: 7.15; 95% confidence interval: 1.20–42.8) in thymic epithelial tumors. In vitro, TGF‐β1 stimulation upregulated PD‐L1 expression in a dose‐dependent manner, accompanied by ...
Chiaki Nakazono +13 more
wiley +1 more source
Models of metaplasticity: a review of concepts
Part of hippocampal or cortical plasticity is characterized by synaptic modifications as a function of the joint activity of the pre- and postsynaptic neurons.
Pierre eYger, Matthieu eGilson
doaj +1 more source
Role for astroglial α1-adrenoreceptors in gliotransmission and control of synaptic plasticity in the neocortex [PDF]
Communication between neuronal and glial cells is thought to be very important for many brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic strength.
Lalo, Ulyana, Pankratov, Yuriy
core +2 more sources
Metaplastic carcinoma of the breast and BRCA1 germline mutation: a case report and review [PDF]
Michiko Yamashita +15 more
openalex +1 more source

