Results 81 to 90 of about 9,287 (251)

Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress

open access: yeseLife, 2018
Glucocorticoid receptor (GR) is crucial for signaling mediated by stress-induced high levels of glucocorticoids. The lateral nucleus of the amygdala (LA) is a key structure underlying auditory-cued fear conditioning.
Ran Inoue   +6 more
doaj   +1 more source

Data mining for the diagnosis of type 2 diabetes [PDF]

open access: yes, 2012
Diabetes is the most common disease nowadays in all populations and in all age groups. diabetes contributing to heart disease, increases the risks of developing kidney disease, blindness, nerve damage, and blood vessel damage.
Andina de la Fuente, Diego   +1 more
core  

Metaplastic LTP inhibition after LTD induction in CA1 hippocampal slices involves NMDA receptor‐mediated neurosteroidogenesis [PDF]

open access: yes, 2013
Long-term depression (LTD) induced by low-frequency electrical stimulation (LFS) in the CA1 region of the hippocampus is a form of synaptic plasticity thought to contribute to learning and memory and to the pathophysiology of neuropsychiatric disorders ...
Izumi, Yukitoshi   +2 more
core   +2 more sources

Molecular pathology of phyllodes tumours of the breast—much more than MED12

open access: yesHistopathology, EarlyView.
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang   +3 more
wiley   +1 more source

NMDA receptor-dependent metaplasticity by high-frequency magnetic stimulation [PDF]

open access: yes, 2014
High-frequency magnetic stimulation (HFMS) can elicit N-methyl-D-aspartate (NMDA) receptor-dependent long-termpotentiation (LTP) at Schaffer collateral-CA1 pyramidal cell synapses.
Kirschstein, Timo   +4 more
core  

Evaluating Cost‐Effectiveness of 85 Endoscopic Surveillance Strategies of Nondysplastic Barrett's Esophagus

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Barrett's esophagus is the known precursor to esophageal adenocarcinoma (EAC), a cancer with poor prognosis. While endoscopic surveillance detects early dysplasia and prevents progression, most Barrett's esophagus patients do not progress to EAC, leading to invasive and costly surveillance.
Ravi Vissapragada   +6 more
wiley   +1 more source

A Model of Fast Hebbian Spike Latency Normalization

open access: yesFrontiers in Computational Neuroscience, 2017
Hebbian changes of excitatory synapses are driven by and enhance correlations between pre- and postsynaptic neuronal activations, forming a positive feedback loop that can lead to instability in simulated neural networks.
Hafsteinn Einarsson   +4 more
doaj   +1 more source

Intraocular Osseous Metaplasia in Norfolk Black Turkey (Meleagris gallopavo): Clinicopathological Characterization of a Rare Avian Condition

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Background Osseous metaplasia is a rare condition characterized by abnormal bone growth in soft tissues. Although documented in mammals, intraocular osseous metaplasia is uncommon in avian species and has been poorly characterized in turkeys (Meleagris gallopavo).
Taina dos Santos Alberti   +6 more
wiley   +1 more source

A Neural Network Approach for Analyzing the Illusion of Movement in Static Images

open access: yes, 2008
The purpose of this work is to analyze the illusion of movement that appears when seeing certain static images. This analysis is accomplished by using a biologically plausible neural network that learned (in a unsupervised manner) to identify the ...
Andina de la Fuente, Diego   +3 more
core  

A State of Mediocrity in Art [PDF]

open access: yes, 2014
Recently, art works that make trajectories in a situation fragmented by postmodernism as a reaction to modernism, have risen. They show trajectory of travels over different time and different space. Allochronic or multiplicity makes it possible.
Takehara, Shinji
core  

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