Results 31 to 40 of about 23,223 (266)

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

mBio, 2022
Human metapneumovirus (HMPV) is a leading cause of respiratory disease among children, immunocompromised individuals, and the elderly. Currently, no vaccines or antivirals are available for the treatment of HMPV infections. ABSTRACT Human metapneumovirus
K. Boggs, Kearstin Edmonds, N. Cifuentes-Muñoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, C. Moncman, T. Creamer, G. Amarasinghe, D. Leung, R. Dutch   +11 more
semanticscholar   +1 more source

CLINICAL AND EPIDEMIOLOGICAL PROFILES OF NOVEL VIRUSES IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN [PDF]

Romanian Journal of Pediatrics, 2015
Viral respiratory tract infections are one of the leading causes of morbidity and mortality in pediatric pathology. The authors provide the latest information on the structure, pathogenesis, clinical features, epidemiology and response to treatment of ...
Alexandru-Ioan Ulmeanu, Carmen Zapucioiu, Coriolan-Emil Ulmeanu   +2 more
doaj   +1 more source

The surge of RSV and other respiratory viruses among children during the second COVID-19 pandemic winter season

Frontiers in Pediatrics, 2023
BackgroundThe non-pharmaceutical measures in the first Covid-19 winter season significantly impacted respiratory pathogens such as RSV, influenza, or metapneumovirus, which cause respiratory infections, especially in infants and young children.
Angela Riepl, Lena Straßmayr, Peter Voitl, Peter Voitl, Paulina Ehlmaier, Julian J. M. Voitl, Klara Langer, Ulrike Kuzio, Alexandra Mühl-Riegler, Bernhard Mühl, Susanne C. Diesner-Treiber   +10 more
doaj   +1 more source

Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance Human metapneumovirus (hMPV) is a major cause of acute lower respiratory traction infection among children, the elderly, and the immunocompromised.
A. Banerjee, Jiachen Huang, S. Rush, J. Murray, Aaron D. Gingerich, Fredejah Royer, C. Hsieh, R. Tripp, J. McLellan, J. Mousa   +9 more
semanticscholar   +1 more source

Human metapneumovirus in paediatric patients [PDF]

Clinical Microbiology and Infection, 2006
Acute respiratory tract infections (ARTIs) are a leading cause of morbidity and mortality in children worldwide, but the aetiology of many ARTIs is still unknown. In 2001, researchers in The Netherlands reported the discovery of a previously unidentified pathogen called human metapneumovirus (hMPV).
N. Principi, S. Bosis, Esposito, Susanna Maria Roberta   +2 more
openaire   +4 more sources

Discovery and Characterization of Novel RNA Viruses in Aquatic North American Wild Birds

Viruses, 2019
Wild birds are recognized viral reservoirs but our understanding about avian viral diversity is limited. We describe here three novel RNA viruses that we identified in oropharyngeal/cloacal swabs collected from wild birds.
Marta Canuti, Ashley N. K. Kroyer, Davor Ojkic, Hugh G. Whitney, Gregory J. Robertson, Andrew S. Lang   +5 more
doaj   +1 more source

Emergence and Potential Extinction of Genetic Lineages of Human Metapneumovirus between 2005 and 2021

mBio, 2022
Human metapneumovirus (HMPV) is one of the major causative agents of human respiratory tract infections. Monitoring of virus evolution could aid toward the development of new antiviral treatments or vaccine designs.
K. Groen, S. van Nieuwkoop, A. Meijer, B. van der Veer, J. V. van Kampen, P. Fraaij, R. Fouchier, B. G. van den Hoogen   +7 more
semanticscholar   +1 more source

COPD Is Associated with Elevated IFN-β Production by Bronchial Epithelial Cells Infected with RSV or hMPV

Viruses, 2021
IFN treatment may be a viable option for treating COPD exacerbations based on evidence of IFN deficiency in COPD. However, in vitro studies have used primarily influenza and rhinoviruses to investigate IFN responses.
Natasha Collinson, Natale Snape, Kenneth Beagley, Emmanuelle Fantino, Kirsten Spann   +4 more
doaj   +1 more source

Human Metapneumovirus Infection among Children Hospitalized with Acute Respiratory Illness

Emerging Infectious Diseases, 2004
Recent studies have associated human Metapneumovirus (HMPV) infection in children with respiratory disease of similar severity as respiratory syncytial virus (RSV) infection.
James A. Mullins, Dean D. Erdman, Geoffrey A. Weinberg, Kathryn M. Edwards, Caroline B. Hall, Frances J. Walker, Marika Iwane, Larry J. Anderson   +7 more
doaj   +1 more source

Zoonotic Origins of Human Metapneumovirus: A Journey from Birds to Humans

Viruses, 2022
Metapneumoviruses, members of the family Pneumoviridae, have been identified in birds (avian metapneumoviruses; AMPV’s) and humans (human metapneumoviruses; HMPV’s).
Sonja T. Jesse, M. Ludlow, A. Osterhaus
semanticscholar   +1 more source