Results 41 to 50 of about 33,445 (250)

Detection of Human Metapneumovirus in Hospitalized Children with Acute Respiratory Tract Infection Using Real-time RT-PCR in a Hospital in Northern Taiwan

Journal of the Formosan Medical Association, 2007
Human metapneumovirus (hMPV) is a newly discovered respiratory pathogen. This prospective hospital-based study investigated the clinical role and features of hMPV in Taiwan.
Pei-Chun Chan, Chung-Yi Wang, Ping-Sheng Wu, Po-Young Chang, Tsao-Ton Yang, Yu-Ping Chiang, Chuan-Liang Kao, Luan-Yin Chang, Chun-Yi Lu, Ping-Ing Lee, Jung-Min Chen, Pei-Lan Shao, Fu-Yuan Huang, Chin-Yun Lee, Li-Min Huang   +14 more
doaj   +1 more source

The global burden of human metapneumovirus-associated acute respiratory infections in older adults: a systematic review and meta-analysis.

The Lancet Healthy Longevity
BACKGROUND The human metapneumovirus (hMPV)-associated disease burden in older adults remains under-researched. We aimed to systematically estimate the global burden of hMPV-associated disease in older adults.
D. Kulkarni, B. Cong, Mamata Jyothish Kumar Ranjini, Geetika Balchandani, Shu-ting Chen, Jingyi Liang, Lina González Gordon, Ajoke Sobanjo-ter Meulen, Xin Wang, You Li, R. Osei-Yeboah, K. Templeton, H. Nair   +12 more
semanticscholar   +1 more source

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Communications Biology, 2023
A conserved allosteric site identified on the L polymerase proteins of RSV and HMPV can be targeted by a dual-specificity, non-nucleoside inhibitor that acts by inhibiting conformational changes necessary for RNA synthesis initiation and elongation ...
Victoria A. Kleiner, Thierry Fischmann, John A. Howe, D. Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel J. Klein, Debbie D Nahas, Bob J. Lucas, He Xi, Edward M Murray, Daphne Y. Ma, Krista Getty, R. Fearns   +14 more
semanticscholar   +1 more source

Human Metapneumovirus Antagonism of Innate Immune Responses

Viruses, 2012
 Human metapneumovirus (hMPV) is a recently identified RNA virus belonging to the Paramyxoviridae family, which includes several major human and animal pathogens.
Xiaoyong Bao, Antonella Casola, Deepthi Kolli   +2 more
doaj   +1 more source

Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus — United States, 2014–2024

MMWR. Morbidity and mortality weekly report
Human metapneumovirus (hMPV) infections cause acute respiratory illness and lower respiratory tract disease. Respiratory syncytial virus (RSV) is a closely related virus within the Pneumoviridae family, and hMPV and RSV infections are associated with ...
Ndey Bassin Jobe, E. Rose, Amber K. Winn, Leah A. Goldstein, Zachary D. Schneider, Benjamin J. Silk   +5 more
semanticscholar   +1 more source

Structural basis for respiratory syncytial virus and human metapneumovirus neutralization

Current Opinion in Virology, 2023
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) continue to be a global burden to infants, the elderly, and immunocompromised individuals.
Rose J. Miller, J. Mousa
semanticscholar   +1 more source

Human metapneumovirus (hMPV) in 2025: emerging trends and insights from community and hospital-based respiratory panel analyses—a comprehensive review

Virology Journal
Human metapneumovirus (hMPV) is a significant respiratory pathogen, primarily impacting young, elderly, and immunocompromised populations. While the clinical presentations are similar to those of other respiratory viruses such as respiratory syncytial ...
Keyhan Mohammadi, Samireh Faramarzi, Shakila Yaribash, Zahra Valizadeh, Erta Rajabi, Mohammad Ghavam, Reza Samiee, Bardia Karim, Mohammadreza Salehi, A. Seifi, Maryam Shafaati   +10 more
semanticscholar   +1 more source

Trends and Challenges in the Surveillance and Control of Avian Metapneumovirus

Viruses, 2023
Among the respiratory pathogens of birds, the Avian Metapneumovirus (aMPV) is one of the most relevant, as it is responsible for causing infections of the upper respiratory tract and may induce respiratory syndromes.
G. B. C. Salles, Giulia Von Tönnemann Pilati, E. Muniz, Antonio Junior de Lima, J. Vogt, Mariane Dahmer, B. Savi, Dayane A. Padilha, G. Fongaro   +8 more
semanticscholar   +1 more source

A Re-emerging Respiratory Virus: Human Metapneumovirus (hMPV)

Cureus
Human metapneumovirus (hMPV) is identified as a pathogenic agent responsible for respiratory tract infections in paediatric, adult and elderly populations.
Baijayantimala Mishra, Diksha Mohapatra, Manisha Tripathy, Prabhudutta Mamidi, P. R. Mohapatra   +4 more
semanticscholar   +1 more source

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins

Nature Communications, 2022
The human metapneumovirus (hMPV) fusion (F) protein is essential for viral entry and is a key target of neutralizing antibodies and vaccine development.
Ching-Lin Hsieh, Scott A. Rush, Concepción Palomo, Chia-Wei Chou, Whitney Pickens, V. Mas, Jason S. McLellan   +6 more
semanticscholar   +1 more source