Results 61 to 70 of about 32,467 (208)

HBsAg-vectored DNA vaccines elicit concomitant protective responses to multiple CTL epitopes relevant in human disease. [PDF]

, 2008
Vaccines capable of controlling neoplastic and infectious diseases which depend on the cellular immune response for their resolution, have proven difficult to develop.
Allan Gould, Dekun Chen, Jacqueline Kattenbelt, Melanie Barnes, Michael Mather, Oscar Haigh, Robert R. Tindle, Scott Thomson   +7 more
core   +1 more source

Application of Metagenomic Next‐Generation Sequencing in the Diagnosis of Pneumonia in Patients With Cancer

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background With the development of new sequencing technologies, metagenomic next‐generation sequencing (mNGS) has become a diagnostic tool for respiratory tract infections. Patients with cancer may develop pneumonia caused by infections or antitumor therapy.
Rong Qin, Chao Wang, Minghua Cong, Le Tian, Ning Li   +4 more
wiley   +1 more source

Human Metapneumovirus Antagonism of Innate Immune Responses

Viruses, 2012
 Human metapneumovirus (hMPV) is a recently identified RNA virus belonging to the Paramyxoviridae family, which includes several major human and animal pathogens.
Xiaoyong Bao, Antonella Casola, Deepthi Kolli   +2 more
doaj   +1 more source

Fianlimab, a human lymphocyte activation gene‐3 monoclonal antibody, in combination with cemiplimab: Tumor‐specific expansion cohorts in advanced malignancies

Cancer, Volume 132, Issue 9, 1 May 2026.
Abstract Background The dose escalation phase of a first‐in‐human (FIH) study demonstrated acceptable safety and preliminary antitumor activity of fianlimab (anti‐lymphocyte activation gene‐3 [LAG‐3]) as monotherapy and in combination with cemiplimab (anti‐programmed cell death‐1 [PD‐1]). Here, the authors present safety and clinical activity data from
Tae Min Kim, Stephen K. Williamson, Kyriakos P. Papadopoulos, Omid Hamid, Grace K. Dy, Ray McDermott, Ariel Birnbaum, John M. Kaczmar, Nehal Lakhani, Danny Rischin, Debashis Sarker, Afshin Dowlati, Xin‐Hua Zhu, Jyoti Malhotra, Jean‐Francois Pouliot, Jayakumar Mani, Laura Brennan, Fang Fang, Shuquan Chen, Mark Salvati, Israel Lowy, Ahmed Khaled, Karl D. Lewis, Glenn Kroog, Matthew G. Fury, Byoung Chul Cho   +25 more
wiley   +1 more source

Genome Sequence of a Divergent Avian Metapneumovirus from a Monk Parakeet (Myiopsitta monachus). [PDF]

, 2019
Here, we report the coding-complete genome sequence of an avian metapneumovirus from a monk parakeet (Myiopsitta monachus), identified by metagenomic next-generation sequencing during an investigation into a disease outbreak in a captive parrot breeding ...
Clubb, Susan, DeRisi, Joseph L, Retallack, Hanna   +2 more
core  

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Clinical evaluation of GenBody hMPV Ag Rapid Test: a diagnostic accuracy study

Annals of Clinical Microbiology
Background: Human metapneumovirus (hMPV) is a major cause of acute respiratory infections in children and adults worldwide; however, no antiviral therapies or vaccines are currently available.
Sungwook Song, Eunsim Shin, Sunghee Han, Sang Gon Lee   +3 more
doaj   +1 more source

Human Metapneumovirus: A Neglected Contributor to Acute Respiratory Infections in Bangladesh: A Public Health Perspective

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Acute respiratory tract infections (ARTIs) are a primary cause of mortality in Bangladesh, yet the Human Metapneumovirus (hMPV) remains critically underdiagnosed. This perspective aims to evaluate the current diagnostic landscape, identify specific surveillance gaps, and propose a prioritized strategic framework for ...
Abdullaha Al Mamun, K. A. M. Inzamul Islam   +1 more
wiley   +1 more source

Seroprevalence of avian metapneumovirus infection in broiler and broiler breeder chickens in Iran

Veterinární Medicína, 2011
Avian metapneumovirus causes an acute highly contagious upper respiratory tract infection primarily of turkeys and chickens. The disease can cause significant economic losses in turkey and chicken flocks, particularly when exacerbated by secondary ...
M. Rahimi
doaj   +1 more source

Sarcoidosis Presenting as Acute Respiratory Distress Syndrome. [PDF]

, 2018
Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory ...
Chan, Vincent, Lashari, Bilal, Raza, Ahmad, Ward, William   +3 more
core   +2 more sources