Results 41 to 50 of about 37,528 (237)

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

open access: yesCommunications Biology, 2023
A conserved allosteric site identified on the L polymerase proteins of RSV and HMPV can be targeted by a dual-specificity, non-nucleoside inhibitor that acts by inhibiting conformational changes necessary for RNA synthesis initiation and elongation ...
Victoria A Kleiner   +14 more
semanticscholar   +1 more source

Discovery and Characterization of Novel RNA Viruses in Aquatic North American Wild Birds

open access: yesViruses, 2019
Wild birds are recognized viral reservoirs but our understanding about avian viral diversity is limited. We describe here three novel RNA viruses that we identified in oropharyngeal/cloacal swabs collected from wild birds.
Marta Canuti   +5 more
doaj   +1 more source

Trends and Challenges in the Surveillance and Control of Avian Metapneumovirus

open access: yesViruses, 2023
Among the respiratory pathogens of birds, the Avian Metapneumovirus (aMPV) is one of the most relevant, as it is responsible for causing infections of the upper respiratory tract and may induce respiratory syndromes.
G. Salles   +8 more
semanticscholar   +1 more source

Human Metapneumovirus Infection among Children Hospitalized with Acute Respiratory Illness

open access: yesEmerging Infectious Diseases, 2004
Recent studies have associated human Metapneumovirus (HMPV) infection in children with respiratory disease of similar severity as respiratory syncytial virus (RSV) infection.
James A. Mullins   +7 more
doaj   +1 more source

Respiratory Viruses in Solid Organ Transplant Recipients

open access: yesViruses, 2021
Solid organ transplantation is often lifesaving, but does carry an increased risk of infection. Respiratory viral infections are one of the most prevalent infections, and are a cause of significant morbidity and mortality, especially among lung ...
Roni Bitterman, Deepali Kumar
doaj   +1 more source

Human Metapneumovirus Infections during COVID-19 Pandemic, Spain

open access: yesEmerging Infectious Diseases, 2023
We describe an unusual outbreak of respiratory infections caused by human metapneumovirus in children during the sixth wave of COVID-19 in Spain, associated with the Omicron variant. Patients in this outbreak were older than usual and showed more hypoxia
M. L. García-García   +7 more
semanticscholar   +1 more source

Whole genome sequencing and evolution analyses of Human metapneumovirus

open access: yesVirus genes, 2023
Human metapneumovirus (HMPV) is a major pathogen of acute respiratory tract infections (ARTIs) in children. Whole genome sequence analyses could help understand the evolution and transmission events of this virus.
Tian-li Wei   +7 more
semanticscholar   +1 more source

Human Metapneumovirus in Adults [PDF]

open access: yesViruses, 2013
Human metapneumovirus (HMPV) is a relative newly described virus. It was first isolated in 2001 and currently appears to be one of the most significant and common human viral infections. Retrospective serologic studies demonstrated the presence of HMPV antibodies in humans more than 50 years earlier.
Lenneke E. M. Haas   +3 more
openaire   +3 more sources

Incidence and viral aetiologies of acute respiratory illnesses (ARIs) in the United States: a population-based study. [PDF]

open access: yes, 2016
We conducted prospective, community-wide surveillance for acute respiratory illnesses (ARIs) in Rochester, NY and Marshfield, WI during a 3-month period in winter 2011.
Albertin, C   +9 more
core   +1 more source

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins

open access: yesNature Communications, 2022
The human metapneumovirus (hMPV) fusion (F) protein is essential for viral entry and is a key target of neutralizing antibodies and vaccine development.
C. Hsieh   +6 more
semanticscholar   +1 more source

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