Results 81 to 90 of about 37,528 (237)

Establishment and application of a quadruple real-time RT-PCR for detecting avian metapneumovirus.

PLoS ONE, 2022
In order to develop an appropriate method for high-throughput detection of avian metapneumovirus, a quadruple real-time reverse-transcription polymerase chain reaction assay was established with four pairs of specific primers and four specific probes ...
Suchun Wang, Nan Jiang, Lijian Jiang, Qingye Zhuang, Qiong Chen, Guangyu Hou, Zhiyu Xiao, Ran Zhao, Yang Li, Chenglong Zhao, Fuyou Zhang, Jianmin Yu, Jinping Li, Hualei Liu, Fuliang Sun, Kaicheng Wang   +15 more
doaj   +1 more source

Comparative analysis of mortality in patients admitted with an infection with influenza A/B virus, respiratory syncytial virus, rhinovirus, metapneumovirus or SARS‐CoV‐2

Influenza and Other Respiratory Viruses
While influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are recognised as a cause of severe illness and mortality, clinical interest for respiratory syncytial virus (RSV), rhinovirus and human metapneumovirus (hMPV ...
Hanneke Boon, A. Meinders, E. V. van Hannen, Matthijs Tersmette, E. Schaftenaar   +4 more
semanticscholar   +1 more source

Structure, Immunogenicity, and Conformation-Dependent Receptor Binding of the Postfusion Human Metapneumovirus F Protein

bioRxiv, 2021
Human metapneumovirus (hMPV) is an important cause of viral respiratory disease. In this paper, we report the X-ray crystal structure of the hMPV fusion (F) protein in the postfusion conformation from genotype B.
Jiachen Huang, Pradeep Chopra, Lin Liu, T. Nagy, J. Murray, R. Tripp, G. Boons, J. Mousa   +7 more
semanticscholar   +1 more source

Prevalence and Diagnostic Challenge of Hemophagocytic Lymphohistiocytosis Syndrome in Critically Ill Patients

European Journal of Haematology, Volume 116, Issue 4, Page 380-390, April 2026.
ABSTRACT Background Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is a severe condition with a challenging diagnosis in the intensive care unit (ICU), for which current recommendations rely on fulfilling five of eight HLH‐2004 criteria.
Claire Queffeulou, Mathieu Bellal, Suzanne Goursaud, Sylvain Chantepie, Damien du Cheyron   +4 more
wiley   +1 more source

Geographical Expansion of Avian Metapneumovirus Subtype B: First Detection and Molecular Characterization of Avian Metapneumovirus Subtype B in US Poultry

Viruses
Avian metapneumovirus (aMPV), classified within the Pneumoviridae family, wreaks havoc on poultry health. It typically causes upper respiratory tract and reproductive tract infections, mainly in turkeys, chickens, and ducks.
M. Luqman, N. Duhan, G. Temeeyasen, Mohamed H. Selim, Sumit Jangra, S. Mor   +5 more
semanticscholar   +1 more source

Emerging Human Metapneumovirus Gene Duplication Variants in Patients with Severe Acute Respiratory Infection, China, 2017–2019

Emerging Infectious Diseases, 2021
We detected human metapneumovirus (HMPV) in 72 (7.1%) of 1,021 patients hospitalized with severe acute respiratory infection in Luohe, China, during 2017–2019. We detected HMPV most frequently in young children and less often in adults. HMPV genotype A2c
Z. Xie, Jin Xu, Yunhui Ren, A. Cui, Hui-ling Wang, Jinhua Song, Qiang Zhang, M. Hu, Wenbo Xu, Yan Zhang   +9 more
semanticscholar   +1 more source

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

PNEUMOVIRUSES IN HUMAN INFECTIOUS DISEASES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
This review presents the actual data about structure, genetic diversity and pathogenicity factors of human respiratory syncytial virus (hRSv) and human metapneumovirus - which are the members of new Pneumoviridae family, according to updated taxonomy ...
S. B. Yatsyshina
doaj   +1 more source

Pathogens detected from patients with acute respiratory infections negative for SARS-CoV-2, Saitama, Japan, 2020

Western Pacific Surveillance and Response, 2023
Objective: During the coronavirus disease pandemic in Japan, all patients with respiratory symptoms were initially tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Kodai Miyashita, Hayato Ehara, Kyoko Tomioka, Hirokazu Fukushima, Tsuyoshi Kishimoto, Asao Honda   +5 more
doaj   +1 more source

Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer

Nature Communications
The prefusion conformation of human metapneumovirus fusion protein (hMPV Pre-F) is critical for eliciting the most potent neutralizing antibodies and is the preferred immunogen for an efficacious vaccine against hMPV respiratory infections.
M. Bakkers, Tina Ritschel, Machteld Tiemessen, Jacobus Dijkman, Angelo A Zuffianò, Xiaodi Yu, Daan van Overveld, L. Le, R. Voorzaat, Marlies M van Haaren, Martijn de Man, S. Tamara, L. van der Fits, R. Zahn, J. Juraszek, Johannes P. M. Langedijk   +15 more
semanticscholar   +1 more source