Results 21 to 30 of about 473 (161)

On the scope of scientific hypotheses

open access: yesRoyal Society Open Science, 2023
Hypotheses are frequently the starting point when undertaking the empirical portion of the scientific process. They state something that the scientific process will attempt to evaluate, corroborate, verify or falsify.
William Hedley Thompson, Simon Skau
doaj   +1 more source

A metric of knowledge as information compression reflects reproducibility predictions for biomedical experiments. [PDF]

open access: yesR Soc Open Sci
Forecasting the reproducibility of research findings is one of the key challenges of metascience. Above-chance predictions have mainly been achieved by pooling the subjective ratings of experts, and how these predictions are formed remains to be ...
Fanelli D, Tan PB, Amaral OB, Neves K.
europepmc   +2 more sources

Pour une « métascience » du paysage

open access: yesProjets de Paysage, 2009
This paper presents a research whose aim is to develop a « metascience » of landscape. It recounts the origins of this program, focusing on the issue of landscapes transmission à hybrid legacy between nature and culture.
Hervé Brunon   +3 more
doaj   +1 more source

Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Lesnik et al., 2016) that described how we intended to replicate selected experiments from the paper ‘Melanoma exosomes educate bone marrow progenitor cells toward a
Jeewon Kim   +6 more
doaj   +1 more source

Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

open access: yeseLife, 2019
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Evans et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Wnt activity defines colon cancer stem cells and is regulated ...
Anthony Essex   +5 more
doaj   +1 more source

One data set, many analysts: Implications for practicing scientists

open access: yesFrontiers in Psychology, 2023
Researchers routinely face choices throughout the data analysis process. It is often opaque to readers how these choices are made, how they affect the findings, and whether or not data analysis results are unduly influenced by subjective decisions.
Erich Kummerfeld, Galin L. Jones
doaj   +1 more source

Melanoma mystery

open access: yeseLife, 2017
Biological variability has confounded efforts to confirm the role of PREX2 mutations in melanoma.
Roger J Davis
doaj   +1 more source

Replication of the natural selection of bad science

open access: yesRoyal Society Open Science, 2023
This study reports an independent replication of the findings presented by Smaldino and McElreath (Smaldino, McElreath 2016 R. Soc. Open Sci. 3, 160384 (doi:10.1098/rsos.160384)). The replication was successful with one exception.
Florian Kohrt   +3 more
doaj   +1 more source

The who, where and how of fusobacteria and colon cancer

open access: yeseLife, 2018
The association between the bacterium Fusobacterium nucleatum and human colon cancer is more complicated than it first appeared.
Cynthia L Sears
doaj   +1 more source

Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

open access: yeseLife, 2020
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Phelps et al., 2016) that described how we intended to replicate selected experiments from the paper ‘Coding-independent regulation of the tumor suppressor PTEN by ...
Hongyan Wang   +3 more
doaj   +1 more source

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