Results 41 to 50 of about 2,288 (193)

Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

eLife, 2019
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li et al., 2015), that described how we intended to replicate selected experiments from the paper ‘The microRNA miR-34a inhibits prostate cancer stem cells and ...
Xuefei Yan, Beibei Tang, Biao Chen, Yongli Shan, Huajun Yang, Reproducibility Project: Cancer Biology   +5 more
doaj   +1 more source

Where next for partial randomisation of research funding? The feasibility of RCTs and alternatives [version 1; peer review: 2 approved]

Wellcome Open Research, 2023
We outline essential considerations for any study of partial randomisation of research funding, and consider scenarios in which randomised controlled trials (RCTs) would be feasible and appropriate.
Tom Stafford, Bilal Mateen, Dan Hind, Ines Rombach, Helen Buckley Woods, James Wilsdon, Munya Dimario   +6 more
doaj   +1 more source

An adversarial collaboration on the rigidity‐of‐the‐right, symmetry thesis, or rigidity‐of‐extremes: The answer depends on the question

Political Psychology, Volume 47, Issue 3, June 2026.
Abstract In an adversarial collaboration, two preregistered U.S.‐based studies (total N = 6181) tested three hypotheses regarding the relationship between political ideology and belief rigidity (operationalized as less evidence‐based belief updating): rigidity‐of‐the‐right, symmetry, and rigidity‐of‐extremes.
Shauna M. Bowes, Cory J. Clark, Lucian Gideon Conway III, Thomas Costello, Danny Osborne, Philip E. Tetlock, Jan‐Willem van Prooijen   +6 more
wiley   +1 more source

The Metaparadigm of Scientific Knowledge and Interdisciplinary Perspectives on Legal Culture

RUDN Journal of Law
The purpose of the research is to assess the prospects for applying methods and approaches from the humanities and exact sciences to understand the genesis, prerequisites, patterns, features, trends, and vectors of the evolution of legal culture as a ...
Maksim V. Zaloilo
doaj   +1 more source

Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs

eLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Kandela et al., 2015) that described how we intended to replicate selected experiments from the paper “Coadministration of a tumor-penetrating peptide ...
Christine Mantis, Irawati Kandela, Fraser Aird, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Known and Unknown Biases: A Framework for Contextualising and Identifying Bias in Animal Behaviour Research

Ethology, Volume 131, Issue 12, Page 269-276, December 2025.
As scientists, we are prone to biases. These biases can influence our ideas, how we conduct our research and how we interpret our findings. Individual researchers can take active steps to locate and mitigate bias in their own work. We propose a matrix of classifying biases which will help researchers contextualise biases.
Lucy A. Winder, Emilie Brignall, Francesca S. E. Dawson Pell, Marion Germain, Chay Halliwell, James A. Hibberd, Fay Morland, Andreas Nord, Mark Sutherland, Jamie E. Thompson, Nicola Hemmings   +10 more
wiley   +1 more source

Unconference–Tool Development in Metascience: Perspectives and Challenges

, 2022
Unconference–Tool Development in Metascience: Perspectives and ...
Marton Kovacs
core   +2 more sources

The readability of scientific texts is decreasing over time

eLife, 2017
Clarity and accuracy of reporting are fundamental to the scientific process. Readability formulas can estimate how difficult a text is to read. Here, in a corpus consisting of 709,577 abstracts published between 1881 and 2015 from 123 scientific journals,
Pontus Plavén-Sigray, Granville James Matheson, Björn Christian Schiffler, William Hedley Thompson   +3 more
doaj   +1 more source

Raising the value of research studies in psychological science by increasing the credibility of research reports: the transparent Psi project

Royal Society Open Science, 2023
The low reproducibility rate in social sciences has produced hesitation among researchers in accepting published findings at their face value. Despite the advent of initiatives to increase transparency in research reporting, the field is still lacking ...
Zoltan Kekecs, Bence Palfi, Barnabas Szaszi, Peter Szecsi, Mark Zrubka, Marton Kovacs, Bence E. Bakos, Denis Cousineau, Patrizio Tressoldi, Kathleen Schmidt, Massimo Grassi, Thomas Rhys Evans, Yuki Yamada, Jeremy K. Miller, Huanxu Liu, Fumiya Yonemitsu, Dmitrii Dubrov, Jan Philipp Röer, Marvin Becker, Roxane Schnepper, Atsunori Ariga, Patrícia Arriaga, Raquel Oliveira, Nele Põldver, Kairi Kreegipuu, Braeden Hall, Sera Wiechert, Bruno Verschuere, Kyra Girán, Balazs Aczel   +29 more
doaj   +1 more source

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

eLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis, Meredith C Edwards, Zachary R Meyers, C Conover Talbot Jr, Haiping Hao, David Blum, Reproducibility Project: Cancer Biology   +6 more
doaj   +1 more source