Results 41 to 50 of about 512 (172)

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

eLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis, Meredith C Edwards, Zachary R Meyers, C Conover Talbot Jr, Haiping Hao, David Blum, Reproducibility Project: Cancer Biology   +6 more
doaj   +1 more source

On “Confirmatory” Methodological Research in Statistics and Related Fields

Statistics in Medicine, Volume 44, Issue 25-27, November 2025.
ABSTRACT Empirical substantive research, such as in the life or social sciences, is commonly categorized into the two modes exploratory and confirmatory, both of which are essential to scientific progress. The former is also referred to as hypothesis‐generating or data‐contingent research, while the latter is also called hypothesis‐testing research. In
F. J. D. Lange, Juliane C. Wilcke, Sabine Hoffmann, Moritz Herrmann, Anne‐Laure Boulesteix   +4 more
wiley   +1 more source

Language barriers in conservation science citation networks

Conservation Biology, Volume 39, Issue 5, October 2025.
Abstract Using relevant scientific evidence is crucial to effectively conserve species and ecosystems worldwide. Currently, evidence that is available only in non‐English languages is severely underutilized. We examined many underutilized non‐English languages in the conservation evidence literature and factors that facilitate the use of non‐English ...
Kelsey Hannah, Richard A. Fuller, Rebecca K. Smith, William J. Sutherland, Tatsuya Amano   +4 more
wiley   +1 more source

How Transparent and Reproducible Are Studies That Use Animal Models of Opioid Addiction?

Addiction Biology, Volume 30, Issue 4, April 2025.
This study assessed transparency, reproducibility and bias minimization practices in animal models of opioid addiction research from 2019 to 2023. Key indices included analysis script sharing, preregistration, masking and randomization, among others. Our findings reveal substantial room for improvement to enhance transparency, reproducibility and the ...
Justine C. Blackwell, Julia Beitner, Alex O. Holcombe   +2 more
wiley   +1 more source

Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

eLife, 2017
In 2015, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Chroscinski et al., 2015) that described how we intended to replicate selected experiments from the paper “The CD47-signal regulatory protein alpha (SIRPa)
Stephen K Horrigan, Reproducibility Project: Cancer Biology   +1 more
doaj   +1 more source

Rethinking GIScience Education in an Age of Disruptions

Transactions in GIS, Volume 29, Issue 2, April 2025.
ABSTRACT GIS and GIScience education have continually evolved over the past three decades, responding to technological advances and societal issues. Today, the content and context in which GIScience is taught continue to be impacted by these disruptions, notably from technology through artificial intelligence (AI) and society through the myriad ...
Amy E. Frazier, Trisalyn Nelson, Peter Kedron, Eric Shook, Somayeh Dodge, Alan Murray, Michael Goodchild, Sarah Battersby, Justine I. Blanford, Christophe Claramunt, Joseph Holler, Caglar Koylu, Angela Lee, Steven Manson, Seda Şalap‐Ayça, John P. Wilson, Bo Zhao, Lauren Bennett, Carmen Cabrera, Rachel Franklin, Grant McKenzie, Harvey Miller, Taylor Oshan, Sergio Rey, Francisco Rowe, Seth Spielman, Wenfei Xu   +26 more
wiley   +1 more source

Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells

eLife, 2018
In 2016, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Vanden Heuvel et al., 2016), that described how we intended to replicate selected experiments from the paper ‘Systematic identification of genomic markers ...
John P Vanden Heuvel, Ewa Maddox, Samar W Maalouf, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Preprocessing choices for P3 analyses with mobile EEG: A systematic literature review and interactive exploration

Psychophysiology, Volume 62, Issue 1, January 2025.
Abstract Preprocessing is necessary to extract meaningful results from electroencephalography (EEG) data. With many possible preprocessing choices, their impact on outcomes is fundamental. While previous studies have explored the effects of preprocessing on stationary EEG data, this research delves into mobile EEG, where complex processing is necessary
Nadine S. J. Jacobsen, Daniel Kristanto, Suong Welp, Yusuf Cosku Inceler, Stefan Debener   +4 more
wiley   +1 more source

Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

eLife, 2020
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Khan et al., 2015), that described how we intended to replicate selected experiments from the paper "A coding-independent function of gene and pseudogene mRNAs ...
John Kerwin, Israr Khan, Reproducibility Project: Cancer Biology   +2 more
doaj   +1 more source

Phenomenology is explanatory: Science and metascience

European Journal of Philosophy, Volume 32, Issue 4, Page 1169-1186, December 2024.
Abstract This essay disambiguates the relationship between phenomenology and explanation, whereby we uncover a fundamentally new way to understand the function of phenomenology within the sciences. These objectives are accomplished in two stages. First, we propose an original way to interpret Husserl's claim that his phenomenology is non‐explanatory ...
Heath Williams, Thomas Byrne
wiley   +1 more source