Results 21 to 30 of about 2,423 (183)

Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Lesnik et al., 2016) that described how we intended to replicate selected experiments from the paper ‘Melanoma exosomes educate bone marrow progenitor cells toward a
Jeewon Kim   +6 more
doaj   +1 more source

Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

open access: yeseLife, 2019
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Evans et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Wnt activity defines colon cancer stem cells and is regulated ...
Anthony Essex   +5 more
doaj   +1 more source

Melanoma mystery

open access: yeseLife, 2017
Biological variability has confounded efforts to confirm the role of PREX2 mutations in melanoma.
Roger J Davis
doaj   +1 more source

One data set, many analysts: Implications for practicing scientists

open access: yesFrontiers in Psychology, 2023
Researchers routinely face choices throughout the data analysis process. It is often opaque to readers how these choices are made, how they affect the findings, and whether or not data analysis results are unduly influenced by subjective decisions.
Erich Kummerfeld, Galin L. Jones
doaj   +1 more source

Replication of the natural selection of bad science

open access: yesRoyal Society Open Science, 2023
This study reports an independent replication of the findings presented by Smaldino and McElreath (Smaldino, McElreath 2016 R. Soc. Open Sci. 3, 160384 (doi:10.1098/rsos.160384)). The replication was successful with one exception.
Florian Kohrt   +3 more
doaj   +1 more source

The who, where and how of fusobacteria and colon cancer

open access: yeseLife, 2018
The association between the bacterium Fusobacterium nucleatum and human colon cancer is more complicated than it first appeared.
Cynthia L Sears
doaj   +1 more source

The Nature of Our Literature

open access: yesCommunications in Kinesiology, 2021
Scientists rely upon an accurate scientific literature in order to build and test new theories about the natural world. In the past decade, observational studies of the scientific literature have indicated that numerous questionable research practices ...
Rosie Twomey   +9 more
doaj   +1 more source

Metascience as a scientific social movement

open access: yesMinerva, 2020
Emerging out of the “reproducibility crisis” in science, metascientists have become central players in debates about research integrity, scholarly communication, and science policy. The goal of this article is to introduce metascience to STS scholars, detail the scientific ideology that is apparent in its articles, strategy statements, and research ...
David Peterson, Aaron Panofsky
openaire   +3 more sources

Replication Study: Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

open access: yeseLife, 2020
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Phelps et al., 2016) that described how we intended to replicate selected experiments from the paper ‘Coding-independent regulation of the tumor suppressor PTEN by ...
Hongyan Wang   +3 more
doaj   +1 more source

Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

open access: yeseLife, 2019
As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Fiering et al., 2015) that described how we intended to replicate selected experiments from the paper ‘Biomechanical remodeling of the microenvironment by stromal ...
Mee Rie Sheen   +6 more
doaj   +1 more source

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