Results 71 to 80 of about 561,058 (309)
Frontiers in Surgery, 2018 BackgroundPositive nodal status (pN1) is an independent predictor of survival in renal cell carcinoma (RCC) patients. However, no study to date has tested whether the location of lymph node (LN) metastases does affect oncologic outcomes in a population ...
Alessandro Nini +20 more
doaj +1 more source
Case Report: All That Glisters Is Not* Cancer
Frontiers in Medicine, 2020 Properly performed staging in non-small-cell lung cancer (NSCLC) is necessary to avoid wrong therapeutic decisions. Here we present a case which manifested as advanced NSCLC but ultimately was composed of two different and rare pathologies.
Claudio Tirelli +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Lymphnodal metastases in endometrial adenocarcinoma.
, 1985 Lymphnodal metastases in endometrial ...
Babilonti L. La Fianza A +2 more
core +1 more source
Acta Veterinaria, 2018 In a study on cytological specimens from 30 cats with histologically confi rmed cutaneous squamous cell carcinoma, the morphometric variables mean nuclear area (MNA, μm2), mean nuclear perimeter (MNP, μm), mean nuclear diameter (D mean, μm), minimum ...
Radostina Simeonov
doaj +1 more source
The Roles of Stroma-Derived Chemokine in Different Stages of Cancer Metastases
Frontiers in Immunology, 2020 The intricate interplay between malignant cells and host cellular and non-cellular components play crucial role in different stages of tumor development, progression, and metastases.
Shahid Hussain +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Radioembolization treatment for liver metastases
, 2017 The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts.
Joanna Kiszka +1 more
core +1 more source
Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]
, 2004 Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A. +5 more
core +1 more source