Results 81 to 90 of about 561,058 (309)

Efeitos farmacológicos da suplementação dietética com arginina em ratos com tumor sólido de Walker 256

Archivos Latinoamericanos de Nutrición, 2000
Os efeitos da suplementação com arginina na dieta de portadores de câncer são controversos. O objetivo deste trabalho é avaliar os efeitos da suplementação dietética com arginina no cresciemnto tumoral, disserninação metastática, metabolismo de ...
M.R.C.G. Novaes, L.A.M. Lima, J.E.G. Ribeiro, A. V. Maga/hães, M. V. Sousa, L. Morhy   +5 more
doaj  

Review of spectral domain-enhanced depth imaging optical coherence tomography of tumors of the retina and retinal pigment epithelium in children and adults

Indian Journal of Ophthalmology, 2015
Background: Spectral domain (SD) enhanced depth imaging optical coherence tomography (EDI-OCT) is a useful tool for anatomic, cross-sectional imaging of retinal conditions.
Carol L Shields, Janet Manalac, Chandana Das, Jarin Saktanasate, Jerry A Shields   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Molecular imaging using positron emission tomography in gastrointestinal malignancy [PDF]

, 2010
Positron Emission Tomography (PET) with 18F-FDG has emerged as a powerful tool in oncology. Furthermore, recent advent of PET/CT and novel tracers are continually expanding its role.
Pakzad, F.
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]

, 2009
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G., Baumann, Anja, Hausmann, Andreas, Boeck, Stefan, Metzeler, Klaus H., Gallmeier, Eike, Stemmler, Hans-Joachim   +6 more
core   +1 more source

Case Report and review of the literature: esophageal pleomorphic rhabdomyosarcoma

Frontiers in Oncology
BackgroundEsophageal rhabdomyosarcoma is an exceedingly rare malignant tumor, with only three cases comprehensively documented in the literature since 1995. Due to its rarity, there is limited information on the epidemiology and diagnosis of this disease,
Matteo Pittacolo, Matteo Pittacolo, Arianna Vittori, Arianna Vittori, Lucia Moletta, Lucia Moletta, Gianpietro Zanchettin, Elisa Sefora Pierobon, Giovanni Capovilla, Renato Salvador, Renato Salvador, Mauro Michelotto, Michele Valmasoni, Michele Valmasoni   +13 more
doaj   +1 more source

Craniocerebral metastases from a supraglottic squamous cell carcinoma: A case report and literature review

Clinical Case Reports, 2019
Craniocerebral metastases as the initial spread of supraglottic squamous cell carcinoma (SCC) are exceptional. The presence of several months' history of dysphagia, dyspnea, cachexia, tobacco/alcohol abuse, and seizure(s) is suspicious of craniocerebral ...
Moisés León‐Ruiz, Julián Benito‐León   +1 more
doaj   +1 more source

In vivo modeling and molecular characterization: a path towards targeted therapy of melanoma brain metastasis

Frontiers in Oncology, 2013
Brain metastasis from melanoma remains mostly incurable and the main cause of death from the disease. Early stage clinical trials and case studies show some promise for targeted therapies in the treatment of melanoma brain metastasis.
Avital eGaziel-Sovran, Avital eGaziel-Sovran, Iman eOsman, Iman eOsman, Eva eHernando, Eva eHernando   +5 more
doaj   +1 more source