Results 101 to 110 of about 561,058 (309)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Parathyroid hormone-related protein and bone metastases

, 2005
This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes.
TJ Martin, C. Jasmin, RE Coleman, CAPANNA, RODOLFO, JA Danks, LR Coia, MA Henderson   +6 more
core  

Recommendations for management of patients with neuroendocrine liver metastases

, 2014
Many management strategies exist for neuroendocrine liver metastases. These strategies range from surgery to ablation with various interventional radiology procedures, and include both regional and systemic therapy with diverse biological, cytotoxic, or ...
Caplin, Martyn, G. Grazi, Dik Kwekkeboom, Russell, Christopher, de Herder, W.W., Stefan Breitenstein, Catherine Klersy, Martyn Caplin, for the Working Group on Neuroendocrine Liver Metastases, Breitenstein, S, Schilsky, Richard, Irvin M. Modlin, Solcia, Enrico, Klersy, C, Russell, C, Siegler, M, Enrico Solcia, Mark Siegler, Kidd, M, Richard Schilsky, Schilsky, R, Lau, Wan-yee, Kwekkeboom, Dik, Andrea Frilling, Frilling, Andrea, Caplin, M, Salem, Riad, Wan-yee Lau, Klersy, Catherine, Davidson, B, Christopher Russell, Kidd, Mark, ), Vilgrain, Valerie, Davidson, Brian, Valerie Vilgrain, Modlin, IM, Modlin, Irvin M, Frilling, A, Solcia, E, Salem, R, Lau, WY, Vilgrain, V, Riad Salem, Siegler, Mark, Breitenstein, Stefan, Mark Kidd, Brian Davidson   +47 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

TRANSFORMACIÓN OSTEOSARCOMATOSA DE TUMOR PHYLLODES MAMARIO

Revista Chilena de Obstetricia y Ginecología, 2008
Antecedentes: El tumor phyllodes (TP) es un tumor poco común y aunque el 34,5-63,7% son benignos, el resto tienen un comportamiento borderline o maligno.
Alejandra Martínez RM, David Hardisson H, Mar Muñoz M, Francisco Gómez P, Javier de Santiago G   +4 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Surgical Treatment of Vertebral Metastases: a Multicentric Study

, 1998
The Surgical Treatment of Vertebral Metastases: a Multicentric ...
GIUDICE V., CAPANNA, RODOLFO, GUIZZARDI G., MORICHI R., OLMEDA A., MICHELIS B., FORMICA C., CAMPANACCI D. A.   +7 more
core  

Imaging Related To Transplantation For Colorectal Liver Metastases

, 2019
In this thesis patients who underwent liver transplantation (LT) for unresectable colorectal liver metastases were studied (SECA study). Lifelong immunosuppression following LT is necessary to prevent organ rejection and the general perception is that ...
Grut, Harald
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source