Results 251 to 260 of about 2,015,361 (384)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

MSLN-mediated activation of EGFR-ERK1/2 signaling drives liver metastasis in breast cancer. [PDF]

Cell Death Discov
Chen J, Lu Z, Zhang G, Meng D, Chang C, Chen J, Wang B, Tong Y, Hai Y, Lei M, Yang X, Gan Y, Deng C, Dai P, Liu M, Tang X.   +15 more
europepmc   +1 more source

Melanoma to papillary thyroid carcinoma: A case of tumor-to-tumor metastasis to the head and neck and a re-evaluation of diagnostic criteria

, 2020
Dennis Curry, Matthew H. Rigby, Martin Bullock   +2 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Integration of circulating biomarkers and clinical factors: construction and validation of a prediction model for lung cancer metastasis. [PDF]

BMC Pulm Med
Qi W, Li Z, Xu J, Wang T.
europepmc   +1 more source

Prostate‐specific antigen nadir within 12 months as an early surrogate marker of biochemical failure and distant metastasis after low‐dose‐rate brachytherapy or external beam radiotherapy for localized prostate cancer

, 2018
Shuichi Nishimura, Toshio Ohashi, Tetsuo Momma, M Sakayori, Takahisa Eriguchi, Tomoki Tanaka, Shoji Yamashita, Takeo Kosaka, Mototsugu Oya, Naoyuki Shigematsu   +9 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Recurrent spinal metastasis of a sporadic medullary carcinoma of the thyroid after radiation therapy: a case report and review of the literature [PDF]

, 2015
Christopher Munoz‐Bendix, Antonio Santacroce, K. Gierga, Frank Floeth, Hans‐Jakob Steiger, Marco Antonio Peñalonzo, Sven Oliver Eicker   +6 more
openalex   +1 more source

EMT, MET, Plasticity, and Tumor Metastasis.

Trends in Cell Biology, 2020
Basil Bakir, Anna M. Chiarella, Jason R. Pitarresi, A. Rustgi   +3 more
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source