Results 251 to 260 of about 1,204,560 (279)
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Leptomeningeal metastasis

Current Opinion in Oncology, 2009
Leptomeningeal metastasis occurs in ~5% of all patients with cancer and is the third most common metastatic complication of the central nervous system. Staging of leptomeningeal metastasis includes contrast-enhanced brain and spine magnetic resonance imaging and radionuclide cerebrospinal fluid (CSF) flow study.
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Biology of metastasis

Cancer, 1986
The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success of failure of therapy, it is in fact a result of a more insidious malignant process termed tumor progression.
Isaiah J. Fidler, Philip Frost
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A Normative Metastasis?

SSRN Electronic Journal, 2020
The article presents the argument that contemporary societies are facing an ever-growing over-production of norms which are chocking its efficient functioning. The argument however is subsequently de-constructed, in particular through a comparative (European vs.
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Planting metastasis early

Nature Reviews Cancer, 2017
Two papers demonstrate that early disseminated cancer cells (DCCs) from HER2+breast cancer are more likely to seed metastasis than those from established tumours.
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Metastasis of metastases

The American Journal of Surgery, 1975
Metastasis of metastases was demonstrated experimentally. Mice whose primary tumors were amputated after the development of pulmonary metastases were placed into parabiosis with normal syngeneic partners. Metastases were demonstrated in the nontumor-bearing partners despite their development of passive immunity.
Herbert C. Hoover, Alfred S. Ketcham
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Treatment of Metastasis

Veterinary Clinics of North America: Small Animal Practice, 1985
Metastasis is the major cause of death in human cancer patients. Understanding the pathogenesis of metastasis will improve the treatment and prognosis of cancer.
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Vertebroplasty for Metastasis [PDF]

open access: possibleMedical Oncology, 2003
Vertebral metastases are frequently asymptomatic; however, the occurrence of a pathological (micro-)fracture may be associated with unremitting pain, instability, and even kyphoscoliotic deformity and require prompt and effective treatment. In symptomatic patients, the beneficial effect of conservative therapies requires too much time.
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Leptomeningeal Metastasis

Cancer Investigation, 2005
Leptomeningeal metastasis is a common complication of cancer. Often the diagnosis can be difficult, but early diagnosis and aggressive treatment can prevent irreversible neurologic deficits. Diagnosis is usually established by the demonstration of malignant cells in the cerebrospinal fluid (CSF) or by the presence of enhancing tumor nodules on cranial ...
Lisa M, DeAngelis, Dina, Boutros
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Mechanisms of Metastasis

Clinical Orthopaedics and Related Research, 1982
The mechanism by which a malignant tumor cell establishes a metastatic foci is a complex process requiring the successful completion of a series of steps. If any step cannot be completed, the entire process fails. The tumor cell must separate from the primary tumor, gain access to an efferent channel (lymphatic or vascular), survive transport to a ...
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Invasion and metastasis

Current Opinion in Oncology, 1992
Tumor metastasis remains a major cause of death for cancer patients. From a clinical perspective, treatment of metastatic disease remains difficult. The initial tumor cell invasive and locomotive events have been completed in many patients by the time of cancer diagnosis and surgery.
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