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CTCs in Metastatic Breast Cancer
2012Circulating tumor cells (CTCs), enumerated by the Food and Drugs Administration-cleared CellSearch(®) system, are an independent prognostic factor of progression-free survival (PFS) and overall survival (OS) in metastatic breast cancer (MBC) patients.
Giordano A., Cristofanilli M.
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Chemotherapy for Metastatic Breast Cancer
Hematology/Oncology Clinics of North America, 2007Cytotoxic chemotherapy is a mainstay of treatment for advanced breast cancer. Treatment of metastatic (also called stage IV, advanced, or recurrent) breast cancer is not considered curative. Rather, the goals of treatment with chemotherapy are to prolong survival, alleviate or prevent tumor-related symptoms or complications, and improve quality of life.
Erica L, Mayer, Harold J, Burstein
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Hypophysectomy in Metastatic Breast Cancer
Archives of Surgery, 1975Experience with 50 women undergoing extracranial transethmoidal-sphenoidal hypophysectomy for metastatic breast carcinoma with 12-month follow-up showed an objective remission of metastases after hypophysectomy in 58% of patients. The highest incidence of remission following the operation occurred in those women with only osseous metastases (83%) or ...
J C, VanGilder, I S, Goldenberg
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Treatment of metastatic breast cancer
Seminars in Oncology Nursing, 1991Relapse of breast cancer connotes a dire prognosis. However, long-term survival with remissions and disease exacerbation are possible using conservative treatment strategies and often sequential hormonal manipulations. Hormonal therapy is the mainstay of metastatic breast cancer treatment for patients with hormonally sensitive tumors; cytotoxic ...
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Metastatic view of breast cancer
Cancer and Metastasis Reviews, 2012The ancient view regarding breast cancer as a metastasis has not been supported so far by experimental evidence. We have implanted nephroblastoma tumor cells resulting in a rat metastatic kidney capsule-parathymic lymph node (PTN) model. India ink implantation confirmed the lymphatic connection between the primary tumor of the kidney and PTNs.
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Living with Metastatic Breast Cancer
2015Although prevalence estimates are imprecise, growing numbers of women in the United States are living longer with metastatic breast cancer, attributable at least in part to the availability of effective targeted therapies. Women living with metastatic disease are understudied, however, and substantial heterogeneity exists in both the clinical ...
Patricia A, Ganz, Annette L, Stanton
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Curing Metastatic Breast Cancer
Journal of Oncology Practice, 2016Metastatic breast cancer is generally considered incurable, and this colors doctor-patient interactions for patients with metastatic disease. Although true for most patients, there appear to be important exceptions, instances where long-term disease-free survival occurs. Although these instances are few in number, they suggest the possibility of cure.
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Gynecologic cancers metastatic to the breast
Journal of the American College of Surgeons, 1998We report a series of gynecologic cancers metastatic to the breast, illustrating the diagnostic and prognostic implications of this rare event.By reviewing the gynecologic oncology data base, we identified 10 women with gynecologic cancer metastatic to the breast who were treated at Indiana University School of Medicine between August 1978 and February
D H, Moore +5 more
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Ovarian cancer metastatic to the breast
Gynecologic Oncology, 2006Metastatic ovarian cancer to the breast should be considered in the differential diagnosis for gynecologic cancer patients with a breast tumor. Despite early detection and treatment, the long-term prognosis for these patients is poor.We present three ovarian cancer patients who developed metastatic ovarian cancer to the breast.
John P, Micha +4 more
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Chemotherapy for metastatic breast cancer
Current Opinion in Obstetrics and Gynecology, 2004This review is intended to summarize the most up-to-date information in the field of chemotherapy for advanced breast cancer.During the past year, the literature on chemotherapy for metastatic breast cancer has focused on three main areas of interest: the development of new cytotoxic agents with most studies addressing the taxane-pretreated population;
Laura, Biganzoli +3 more
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