Results 281 to 290 of about 376,342 (317)

Treatment of Metastatic Breast Cancer

Journal of the National Comprehensive Cancer Network, 2014
Many newer agents in combination are being studied in the front-line treatment of women with HER2-positive metastatic breast cancer (MBC), but the story in the endocrine arena is more about the wise use of new strategies to overcome endocrine resistance, because no new antihormonal agents have been approved in the past decade.
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Therapy for metastatic breast cancer

Current Opinion in Oncology, 1994
Our understanding of mechanisms of resistance to endocrine treatment has increased; they include mutations in steroid receptors and altered metabolism of tamoxifen. Tamoxifen and progestogens appear to have similar efficacies for first-line endocrine treatment, but high doses of progestogens have been shown to give less cost-effective results compared ...
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Vulvar cancer metastatic to the breast

Gynecologic Oncology, 2006
Vulvar cancer rarely sends metastases to distant sites.A 49-year-old female presented with a vulvar mass. The histologic examination revealed an infiltrating lesion with free surgical margins and no evidence of lymph node involvement. Four months following surgery, due to a bloody breast discharge and a palpable breast lump an excisional biopsy was ...
D, Vicus, J, Korach, E, Friedman, S, Rizel, G, Ben-Baruch   +4 more
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Ovarian cancer metastatic to the breast

Gynecologic Oncology, 1986
The breast is an uncommon site for metastasis from epithelial ovarian cancer. Such lesions are purportedly secondary to blood-borne metastases. The accurate classification of ovarian epithelial neoplasms is the cornerstone of decisions regarding therapy and prognosis.
S, Laifer, J, Buscema, T H, Parmley, N B, Rosenshein   +3 more
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Breast cancer metastatic to the vulva

Gynecologic Oncology, 2004
Primary cancer of the vulva is not common, constituting only 3-5% of all gynecologic malignancies and
Shyr-Ming, Sheen-Chen, Hock-Liew, Eng, Chao-Cheng, Huang   +2 more
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Cutaneous Metastatic Breast Cancer

Clinical Journal of Oncology Nursing, 2002
Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of cancer deaths among women in the United States. Many women diagnosed with breast cancer will achieve a cure with surgery followed by adjuvant chemotherapy, hormonal therapy, or radiation therapy; however, some breast cancer survivors will develop locally ...
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Update on metastatic breast cancer

Current Oncology Reports, 1999
Although the great majority (80%) of patients diagnosed with breast cancer have disease that is limited to a locoregional area (breast and/or axillary lymph nodes), almost half of them eventually develop metastatic disease. An extensive array of basic and clinical research has been performed throughout the last decade in an attempt to improve the ...
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Gemcitabine in metastatic breast cancer

Expert Review of Anticancer Therapy, 2005
Gemcitabine is a pyrimidine antimetabolite which has shown activity in metastatic breast cancer both as a single agent, but also in various combination regimens. It is characterized by a unique mechanism of action which includes cytotoxic self-potentiation, masked DNA chain termination and potent inhibition of DNA repair.
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Cytopathology of Metastatic Breast Cancer

Clinical Breast Cancer, 2000
A 52-year-old woman developed an infiltrating ductal carcinoma of the breast 16 years after being treated for comedocarcinoma of the left breast. Although the tumor was high grade with lymphatic space invasion and incompletely excised, the patient declined adjunctive therapy.
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The biology of metastatic breast cancer

Cancer, 1990
Early detection and surgical removal of breast cancer are most effective in managing a disease that may affect up to one in ten women in North America and Western Europe. However, one of the most important prognostic indicators for breast cancer is the presence of neoplastic cells in the axillary lymph nodes.
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