Results 11 to 20 of about 309,141 (294)

Factors influencing choice of chemotherapy in metastatic colorectal cancer (mCRC) [PDF]

, 2013
Management of metastatic colorectal cancer requires a multimodal approach and must be performed by an experienced, multidisciplinary expert team. The optimal choice of the individual treatment modality, according to disease localization and extent, tumor
BASSO, ENRICO, CARUSO, DAVIDE, EVANGELISTA, SALVATORE, Foteini Vakiarou, G. Rinaldi, L. Bianchi, Lo Russo, Giuseppe, PAPA, ANSELMO, Perrone-congedi, Francesca, PRETE, ALESSANDRA ANNA, ROSSI, Luigi, SPINELLI, GIAN PAOLO, Stati, Valeria, TOMAO, SILVERIO, VERRICO, MONICA, ZORATTO, federica   +15 more
core   +1 more source

Long non-coding RNAs CCAT1 and CCAT2 in colorectal liver metastases are tumor-suppressive via MYC interaction and might predict patient outcomes.

PLoS ONE, 2023
BackgroundLiver metastases severely reduce the long term survival of colorectal cancer patients. Long non-coding RNAs (lncRNAs) CCAT1 and CCAT2 have previously been found to be associated with impaired patient outcomes in primary colorectal cancer.
Clemens Franz, Michael Wuehrl, Sibylle Hartmann, Fee Klupp, Thomas Schmidt, Martin Schneider   +5 more
doaj   +3 more sources

Second line anti-cancer therapy for metastatic colorectal cancer: treatment strategy

Медицинский совет, 2015
Colorectal cancer is one of the most widespread cancers globally. Over the past decade, there has been a significant progress in the treatment of metastatic colorectal cancer.
K. A. Vorontsova, N. V. Dobrova, G. V. Vyshinskaya   +2 more
doaj   +1 more source

Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland [PDF]

, 2015
background:  Population colorectal cancer screening programmes have been introduced to reduce cancer-specific mortality through the detection of early-stage disease.
A Downing, C von Wagner, CG Fraser, CS McArdle, CS Roxburgh, CS Roxburgh, D Mansouri, DC McMillan, EJ Morris, G Libby, H Gunnarsson, H Gunnarsson, HL Kelsall, JE Crozier, JH Anderson, JH Scholefield, JH Scholefield, JS Mandel, K Skala, KK Alexiusdottir, LH Sobin, O Kronborg, R Oliphant, R Oliphant, RJ Steele, RJ Steele, S Biondo, SJ Goodyear, SK Wong   +28 more
core   +2 more sources

Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab [PDF]

, 2015
Background: The aim of our study was to evaluate whether a panel of biomarkers, prospectively analysed might be able to predict patients' clinical outcome more accurately than RAS status alone.
Abouelkhair, KM, Cascinu, S, Del Prete, M, Faloppi, L, Giampieri, R, Ibrahim, EM, Loretelli, C, Mandolesi, A, Maristella, B, Scarpelli, M, Scartozzi, M   +10 more
core   +3 more sources

Thumb metastases in a patient with colorectal cancer [PDF]

Archive of Oncology, 2007
Bone metastases from colorectal cancer are not common and most frequently are manifesting in late history of metastatic disease. We present a 67-old man who had first symptoms of metastatic disease manifested with edema and decreased mobility of thumb of
Nikolić Ivan, Patrnogić Aleksandar, Stojiljković Bratislav, Bogdanović Bogdan, Kukić Biljana   +4 more
doaj   +1 more source

RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. [PDF]

, 2013
ObjectiveTo determine the impact of RAS mutation status on survival and patterns of recurrence in patients undergoing curative resection of colorectal liver metastases (CLM) after preoperative modern chemotherapy.BackgroundRAS mutation has been reported ...
Aloia, Thomas A, Andreou, Andreas, Chen, Su S, Curley, Steven A, Kopetz, Scott E, Maru, Dipen M, Shindoh, Junichi, Vauthey, Jean-Nicolas, Zimmitti, Giuseppe   +8 more
core   +1 more source

Consistent expression of guanylyl cyclase-C in primary and metastatic gastrointestinal cancers. [PDF]

PLoS ONE, 2017
The transmembrane receptor guanylate cyclase-C (GCC) has been found to be expressed in colorectal cancers. However, limited data are available on GCC protein expression in non-colorectal gastrointestinal tumors and few studies have reported whether GCC ...
Hadi Danaee, Thea Kalebic, Timothy Wyant, Matteo Fassan, Claudia Mescoli, Feng Gao, William L Trepicchio, Massimo Rugge   +7 more
doaj   +1 more source

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources

Circulating extracellular vesicle-derived MARCKSL1 is a potential diagnostic non-invasive biomarker in metastatic colorectal cancer patients

Scientific Reports, 2023
Extracellular vesicle-derived proteins are closely related to colorectal cancer metastasis, and early detection and diagnosis of colorectal cancer metastasis is very important to improve the prognosis.
Wenqing Rong, Shiyun Shao, Yunzhou Pu, Qing Ji, Huirong Zhu   +4 more
doaj   +1 more source