Results 91 to 100 of about 885,175 (334)

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Treatment of Metastatic Uveal Melanoma: Systematic Review [PDF]

, 2020
Cristina Rodríguez-Vidal, Daniel Fernández‐Díaz, Beatriz Fernandez-Marta, Nerea Lago‐Baameiro, María Pardo, Paula Silva, Laura Paniagua, María José Blanco‐Teijeiro, Antonio Piñeiro, Manuel F. Bande   +9 more
openalex   +1 more source

Supplementary Figure 4 from Regulation of CD4⁺NKG2D⁺ Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering [PDF]

, 2023
Ana I. Romero, Nathalie Chaput, Vichnou Poirier-Colame, Sylvie Rusakiewicz, Nicolas Jacquelot, Kariman Chaba, Erwan Mortier, Yannick Jacques, Sophie Caillat‐Zucman, Caroline Flament, Anne Caignard, Meriem Messaoudene, Anne Aupérin, Philippe Vielh, Philippe Dessen, Camillo Porta, Christine Mateus, Maha Ayyoub, Danila Valmori, Alexander Eggermont, Caroline Robert, Laurence Zitvogel   +21 more
openalex   +1 more source

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma

Annals of Oncology, 2018
Background Clinical trials have recently evaluated safety and efficacy of neoadjuvant therapy among patients with surgically resectable regional melanoma metastases. To capture informative prognostic data connected to pathological response in such trials,
M. Tetzlaff, Jane L. Messina, Julie E. Stein, Xiaowei Xu, R. Amaria, C. U. Blank, B. Wiel, P. Ferguson, R. Rawson, M. I. Ross, A. Spillane, J. Gershenwald, R. Saw, A. V. Akkooi, W. Houdt, Tara C Mitchell, A. Menzies, G. Long, J. Wargo, Michael A. Davies, Victor G. Prieto, J. Taube, R. Scolyer   +22 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Hospitalisation costs of metastatic melanoma in France; the MELISSA study (MELanoma In hoSpital coSts Assessment)

BMC Health Services Research, 2017
Background Management of metastatic melanoma is changing rapidly following the introduction of innovative effective therapies, with consequences for the allocation of healthcare resources.
Jérôme Fernandes, Bruno Bregman, Patrick Combemale, Camille Amaz, Lucie de Léotoing, Alexandre Vainchtock, Anne-Françoise Gaudin   +6 more
doaj   +1 more source

Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma

Scientific Reports, 2018
A prospective study explored the heterogeneous nature of metastatic melanoma using Multiplex immunohistochemistry (IHC) and flow cytometry (FACS). Multiplex IHC data quantitated immune subset number present intra-tumoral (IT) vs the tumor stroma, plus ...
H. Halse, A. Colebatch, P. Petrone, Michael A Henderson, J. Mills, H. Snow, J. A. Westwood, S. Sandhu, S. Sandhu, J. Raleigh, A. Behren, Jonathan Cebon, P. Darcy, Phillip K. Darcy, M. Kershaw, M. Kershaw, G. McArthur, D. Gyorki, D. Gyorki, P. Neeson, P. Neeson   +20 more
semanticscholar   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Resection of a Recurrent Metastatic Leptomeningeal Melanoma: Case Report and Literature Review

, 2023
Nyoman Golden, Marleen Marleen, Made Bhuwana Putra, Marthinson Andrew Tombeng, I Gusti Ngurah Dharma Kesuma, Denny Japari, Ni Putu Sriwidyani, Yosi Wanda Kusuma, Jevon Indra Susanto   +8 more
openalex   +1 more source