Results 171 to 180 of about 885,175 (334)

Association of oncogene mutations with clinical and histopathological characteristics in patients with metastatic melanoma. [PDF]

An Bras Dermatol
Quintiliano JA, Nunes AF, Pinheiro-Hubinger-Stauffer L.   +2 more
europepmc   +1 more source

Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma [PDF]

, 2018
Muhammad Zubair Afzal, Rima R. Mercado, Keisuke Shirai   +2 more
openalex   +1 more source

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

Nature Medicine, 2018
Noam Auslander, Gao Zhang, J. Lee, Dennie T. Frederick, B. Miao, Tabea Moll, Tian Tian, Zhi Wei, Sanna Madan, R. Sullivan, G. Boland, K. Flaherty, M. Herlyn, E. Ruppin   +13 more
semanticscholar   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

A case of "buckshot" metastatic melanoma: A rare and aggressive pattern of cutaneous spread. [PDF]

SAGE Open Med Case Rep
Werpachowski N, Carr C.
europepmc   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Metastatic melanoma presenting with gastrointestinal bleeding and a gastric mass. [PDF]

Gastroenterol Rep (Oxf)
Martini M, Garg M, Deeb Y, Rajamanuri M.
europepmc   +1 more source

Targeting the Cellular Signaling: BRAF Inhibition and Beyond for the Treatment of Metastatic Malignant Melanoma [PDF]

, 2011
Felipe Ades, Otto Metzger
openalex   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma. [PDF]

Chem Biodivers
Maphutha J, Twilley D, Dawood M, Efferth T, Efferth T, Lall N.   +5 more
europepmc   +1 more source