Results 181 to 190 of about 885,175 (334)

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Systemic Sarcoidosis Mimicking Metastatic Melanoma: Unveiling the Masquerade. [PDF]

Cureus
Chee SY, Goodman D, Nolan A, Kelly J.
europepmc   +1 more source

Hypercalcemia as an Immune‐Related Adverse Event in a Patient Receiving Nivolumab and Ipilimumab for Metastatic Melanoma: A Case Report [PDF]

Sam Plessers, Jeroen Mebis, Nina De Moor, Tim Wessels, Daisy Luyten, Annelies Requilé   +5 more
openalex   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Metastatic Melanoma in a Retinoblastoma Survivor: Can Immunohistochemistry Save the Day? [PDF]

Cureus
Nurla LA, Așchie M, Orășanu CI, Boșoteanu M.   +3 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Liver failure due to metastatic melanoma: A case report. [PDF]

World J Clin Cases
Domislovic V, Sesa V, Kosuta I, Bulimbasic S, Mrzljak A.   +4 more
europepmc   +1 more source

Metastatic Melanoma of Unknown Primary

, 2023
Dehhaze Adil, Daghouri Nada- Imane, Labbaci Rim, Taybi Otmane, Diher Issam, Tazi Hanae, Echmili Mouad, Mai Aisha, Barij Hamza, Bouazza Omar, Mahioui Mimoun   +10 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A Rare Presentation of Cystic Metastatic Melanoma in the Upper Chest. [PDF]

Case Rep Dermatol Med
Tchack M, Musolff N, Wolfe S, Sandeep R, Rao B.   +4 more
europepmc   +1 more source