Results 211 to 220 of about 885,175 (334)

Fatal Toxic Megacolon Following Nivolumab and Ipilimumab Therapy in Metastatic Melanoma: A Case Report [PDF]

Hideki Fujiwara, Takuya Maeda, Takehiko Katsurada, Hideyuki Ujiie   +3 more
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Case Report: Multiple immune related adverse events in a patient with metastatic melanoma. [PDF]

Front Immunol
Varada NL, Yang O, Savage DJ.
europepmc   +1 more source

Immune checkpoint inhibition in metastatic or non-resectable melanoma after failure of adjuvant anti-PD-1 treatment. A EUMelaReg real-world evidence study

Michael Weichenthal, Eva Ellebæk, Joanna Mangana, Nethanel Asher, Iva Gavrilova, Lidija Kandolf Sekulović, Selma Ugurel, Axel Hausschild, Friedegund Meier, Ulrike Leiter, Elisabeth Livingstone, Christoffer Gebhardt, Ralf Gutzmer, Christina H. Ruhlmann, Louise Mahncke-Guldbrandt, Charlotte Aaquist Haslund, Sylwia Kopeć, Paweł Teterycz, Marc Bender, Wilfried Poudroux, Eva Muñoz‐Couselo, Miguel‐Ángel Berciano‐Guerrero, Gergana Shalamanova, Danielle K. DePalo, Jasmina Marić-Brozić, Vanna Chiarion‐Sileni, Ana Arance, Dimitrios C. Ziogas, Caroline Robert, Anthonie O. van de Velde, Awa A. Gassama, Ronnie Shapira, Guy Ben‐Betzalel, Shirly Grynberg, Egle Ramelyte, Fabio Bertoldo, Valerio DelPrete, Caroline Gaudy‐Marqueste, Peter Mohr, Reinhard Dummer, Paolo A. Ascierto, Helen Gogas, Enrique Espinosa, Célèste Lebbé, Piotr Rutkowski, John B.A.G. Haanen, Dirk Schadendorf, Inge Marie Svane   +47 more
openalex   +2 more sources

EXTH-25. Highly potent drug candidate for the treatment of brain metastatic lung cancer and melanoma [PDF]

Waldemar Debinski, Kyle D. Fink, Ryan T. Mott, Samara Hailey, Denise Herpai   +4 more
openalex   +1 more source

Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma

Annals of Oncology, 2017
Jenny H. Lee, Jenny H. Lee, G. Long, Suzanah C. Boyd, S. Lo, A. Menzies, V. Tembe, A. Guminski, V. Jakrot, R. Scolyer, R. Scolyer, Graham J. Mann, R. Kefford, M. Carlino, H. Rizos   +14 more
semanticscholar   +1 more source

MR‐DELTAnet: A Longitudinal MRI‐Transformer Model Predicting Pathological Complete Response and Revealing Immune Microenvironment via scRNA‐seq in Locally Advanced Rectal Cancer

Advanced Science, EarlyView.
The MR‐DELTAnet model utilizes longitudinal MRI to predict treatment response after neoadjuvant chemoradiotherapy in locally rectal cancer patients, accurately identifying patients likely to achieve pathological complete response for personalized management.
Wuteng Cao, Huaxian Chen, Jiao Li, Yihui Zheng, Liqing Xie, Guozhong Xiao, Zeyan Wang, Fen Yuan, Junhong Chen, Chongbao Sun, Jing Dai, Jinping Zeng, Xinhua Wang, Lei Wu, Hongcheng Lin   +14 more
wiley   +1 more source

What Is the Role of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade in Patients with Metastatic Melanoma? [PDF]

, 2009
Caroline Robert, François Ghiringhelli
openalex   +1 more source

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

Metastatic melanoma to the orbit masquerading as idiopathic orbital inflammation: a case report. [PDF]

Front Ophthalmol (Lausanne)
Fernandes JJ, Sharabura AB, Pfannenstiel MM, Sokol JA.   +3 more
europepmc   +1 more source