Results 21 to 30 of about 284,307 (179)
Biomedicines, 2022 Metastatic melanoma is a highly malignant tumor. Melanoma cells release extracellular vesicles (EVs), which contribute to the growth, metastasis, and malignancy of neighboring cells by transfer of tumor-promoting miRNAs, mRNA, and proteins.
Maxim L. Bychkov +7 more
doaj +1 more source
Pigmented melanoma cell migration study on murine syngeneic B16F10 melanoma cells or tissue transplantation models [PDF]
, 2019 Melanoma is a lethal form of skin cancer with poor prognosis, especially due to the early metastatic feature. Recent studies have shown that the melanin pigment influences the nanomechanical properties and, therefore, the metastatic behavior of the ...
Buteică, Sandra Alice +5 more
core +2 more sources
Biochemistry and Biophysics Reports, 2023 Nicotinic acetylcholine receptors (CHRNs) expression and their critical role in various types of cancer have been reported. However, it is still unclear which CHRNs and their associated genes play essential roles in metastasis in melanoma patients. Here,
Mohamed Nabil Bakr +2 more
doaj +1 more source
Medical Sciences, 2022 Molecular and histopathological analysis of melanoma subtypes has revealed distinct epidemiological, genetic, and clinical features. However, immunotherapy for advanced metastatic melanoma patients does not differ based on subtype.
Charlotte Andrieu +10 more
doaj +1 more source
SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma [PDF]
, 2018 Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread.
Bellenghi, Maria +8 more
core +1 more source
IPILIMUMAB IN THERAPY OF METASTATIC MELANOMA
Медицинский совет, 2016 Metastatic melanoma remains a refractory disease. Great progress in therapy of metastatic melanoma patients has been made in the recent five years. Targeted immunotherapy – a selective effect on lymphocytes signal molecules - became a principally new ...
I. V. SAMOILENKO +2 more
doaj +1 more source
The usefulness of c-Kit in the immunohistochemical assessment of melanocytic lesions [PDF]
, 2011 C-Kit (CD117), the receptor for the stem cell factor, a growth factor for melanocyte migra- tion and proliferation, has shown differential immunostaining in various benign and malig- nant melanocytic lesions. The purpose of this study is to compare c-Kit
Atzori L +9 more
core +1 more source
BMC Cancer, 2018 Background Immunotherapies have advanced the treatment of metastatic melanoma; however, they are associated with immune-related toxicities. Patients with pre-existing autoimmune comorbidities are commonly excluded from clinical trials investigating ...
Qiufei Ma +5 more
doaj +1 more source
MicroRNAs in melanoma development and resistance to target therapy [PDF]
, 2017 microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio +7 more
core +1 more source
Indirect treatment comparison of dabrafenib plus trametinib versus vemurafenib plus cobimetinib in previously untreated metastatic melanoma patients. [PDF]
, 2017 BackgroundMetastatic melanoma is an aggressive form of skin cancer with a high mortality rate and the fastest growing global incidence rate of all malignancies.
Ahuja, Amit +4 more
core +2 more sources