Results 301 to 310 of about 885,175 (334)
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Angiomatoid Metastatic Melanoma
Dermatologic Surgery, 2004Two patients with metastatic melanoma, both with the same bizarre morphology and an unusual, comparatively benign course, are described: a 50-year-old female who more than 20 years after a primary melanoma on the right upper arm, Clark level III, maximum tumor thickness of 1.1 mm, developed multiple metastases in the deep soft tissue and a 62-year-old ...
Bettina G, Zelger, Bernhard, Zelger
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Pathology Case Reviews, 2015
Abstract Transformation into melanoma is thought to occur due to the accumulation of mutations in growth-regulating genes, the loss of adhesion receptors, and the increase in autocrine and paracrine growth factors; all of which contribute to uncontrolled proliferation promoting the survival of these abnormal cells.
Kathryn Baksh, Ragini R. Kudchadkar
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Abstract Transformation into melanoma is thought to occur due to the accumulation of mutations in growth-regulating genes, the loss of adhesion receptors, and the increase in autocrine and paracrine growth factors; all of which contribute to uncontrolled proliferation promoting the survival of these abnormal cells.
Kathryn Baksh, Ragini R. Kudchadkar
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Ophthalmology Clinics of North America, 2005
Despite achieving great accuracy in correctly diagnosing uveal melanoma in the United States, mortality owing to this tumor has remained unchanged over a period of 25 years from 1973 to 1997. In general, the survival with metastatic uveal melanoma is poor, with a median survival of less than 6 months.
Arun D, Singh, Ernest C, Borden
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Despite achieving great accuracy in correctly diagnosing uveal melanoma in the United States, mortality owing to this tumor has remained unchanged over a period of 25 years from 1973 to 1997. In general, the survival with metastatic uveal melanoma is poor, with a median survival of less than 6 months.
Arun D, Singh, Ernest C, Borden
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Inflammatory metastatic melanoma
Journal of Cutaneous Pathology, 1999An 87‐year‐old woman developed erythema, induration and tenderness of the skin overlying each breast. One year before, she had undergone an axillary lymph node dissection because of metastases from melanoma. The primary site was unknown. A skin biopsy showed pigmented tumor nests within the dermal lymphatic vessels, and immunohistochemistry confirmed ...
A, Flórez +4 more
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New England Journal of Medicine, 2019
Metastatic Uveal Melanoma A 59-year-old woman presented with inflammation and pain in the right eye. Magnetic resonance imaging showed a right orbital mass.
Lesley, Everett, Thomas, Copperman
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Metastatic Uveal Melanoma A 59-year-old woman presented with inflammation and pain in the right eye. Magnetic resonance imaging showed a right orbital mass.
Lesley, Everett, Thomas, Copperman
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American Journal of Health-System Pharmacy, 2008
New medications and combination treatment strategies for patients with metastatic melanoma are discussed.Bcl-2 is an inhibitor of apoptosis that is overexpressed in approximately 80% of melanoma cell lines and is believed to contribute to the development of resistance to cytotoxic chemotherapy in patients with melanoma.
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New medications and combination treatment strategies for patients with metastatic melanoma are discussed.Bcl-2 is an inhibitor of apoptosis that is overexpressed in approximately 80% of melanoma cell lines and is believed to contribute to the development of resistance to cytotoxic chemotherapy in patients with melanoma.
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Metastatic melanoma: Chemotherapy
Seminars in Oncology, 2002The incidence of cutaneous melanoma has been rapidly increasing, with an estimate of 47,700 new cases diagnosed in 2000 in the United States. In the early phase of its natural history, melanoma is cured in most cases by surgery, but once the metastatic phase develops, it is almost always fatal.
Emilio, Bajetta +9 more
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Annual Review of Medicine, 2012
Metastatic melanoma has historically been one of the most treatment-refractory types of cancer. Recent headway has been made in understanding the genetic underpinnings of this cancer. A subset of oncogenic events is amenable to targeting with drug therapy.
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Metastatic melanoma has historically been one of the most treatment-refractory types of cancer. Recent headway has been made in understanding the genetic underpinnings of this cancer. A subset of oncogenic events is amenable to targeting with drug therapy.
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American Journal of Ophthalmology, 1978
We studied the metastatic pattern of 41 patients initially referred with a primary choroidal melanoma who later developed widespread disease. In the order of frequency, the most common sites of metastatic involvement were the liver (56%), subcutaneous tissue (36.5%), and bone (7%).
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We studied the metastatic pattern of 41 patients initially referred with a primary choroidal melanoma who later developed widespread disease. In the order of frequency, the most common sites of metastatic involvement were the liver (56%), subcutaneous tissue (36.5%), and bone (7%).
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