Results 61 to 70 of about 284,307 (179)

Identification of IL10RA by Weighted Correlation Network Analysis and in vitro Validation of Its Association With Prognosis of Metastatic Melanoma

Frontiers in Cell and Developmental Biology, 2021
Skin cutaneous melanoma (SKCM) is the major cause of death for skin cancer patients, its high metastasis often leads to poor prognosis of patients with malignant melanoma.
Si Cheng, Si Cheng, Zhe Li, Wenhao Zhang, Zhiqiang Sun, Zhigang Fan, Judong Luo, Hui Liu   +7 more
doaj   +1 more source

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis. [PDF]

, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Akslen, Albino, Anissa Chikh, Antonio Costanzo, Arima, Arnoult, Avery-Kiejda, Avery-Kiejda, Azzola, Bae, Baisden, Bardeesy, Belmar-Lopez, Benchimol, Bourne, Brinck, Burford, Bártek, Catherine A. Harwood, Chan, Charlotte M. Proby, Chehab, Chipuk, Chipuk, Choi, Colombari, Daniele Bergamaschi, David Mesher, Dellavalle, Dhillon, Di Como, Dotto, el-Deiry, Fenouille, Flores, Flores, Francesca Moretti, Fukushima, Gembarska, Giovanna Chiorino, Glusac, Gomez-Monterrey, Gressner, Hameed, Harmes, Hibi, Hirao, Hocker, Hoek, Houben, Hu, Hussein, Ikawa, Irene M. Leigh, Jacobs, Ji, Kakudo, Kanner, Kanoko, Karst, Katoh, Keyes, Kilic, Knopf, Koga, Koster, Kulesz-Martin, Lassam, Leverrier, Li, Liefer, Little, MacPartlin, Mancini, Mangiulli, Manuela Graf, Marchenko, Marchini, Maria Scatolini, Massion, Matsuoka, McGregor, Merlino, Michaelis, Mihara, Mills, Moll, Morgan, Mundt, Muthusamy, Müller, Narahashi, Nemajerova, Oda, Okada, Osada, Paolo Sanza’, Perez-Losada, Petitjean, Polsky, Prince, Reis-Filho, Reis-Filho, Ribeiro-Silva, Riley, Rino Cerio, Rocca, Rocco, Rubeta N. Matin, Sakiz, Sansome, Sato, Satyamoorthy, Scatolini, Schilling, Seitz, Senoo, Senoo, Serber, Shieh, Shields, Smalley, Sparrow, Stephanie Law Pak Chong, Stretch, Suh, Tokuyasu, Tuve, Valentina Senatore, Vance, Verhaegen, Walerych, Walerych, Weiss, Westfall, Whitesell, Wäster, Yamamoto, Yamamoto, Yang, Yang, Yaziji, Zangen, Zerp   +143 more
core   +1 more source

Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review

Chinese Journal of Cancer, 2017
Metastatic melanoma has long been considered to have a very poor prognosis and to be chemo-resistant. However, a subgroup of patients with metastatic melanoma presents remarkable responses to chemotherapeutic agents, even in the absence of a response to ...
Aurélien Simon, Hampig Raphael Kourie, Joseph Kerger   +2 more
doaj   +1 more source

Blood‐Lymphatic Integrated System with Heterogeneous Melanoma Spheroids via In‐Bath Three‐Dimensional Bioprinting for Modelling of Combinational Targeted Therapy

Advanced Science, 2022
Although metastatic melanoma can be managed with chemotherapy, its heterogeneity and resistance to therapy remain poorly understood. In addition to the spread of melanoma in the bloodstream, melanoma‐stroma interaction and the lymphatic system play ...
Won‐Woo Cho, Minjun Ahn, Byoung Soo Kim, Dong‐Woo Cho   +3 more
doaj   +1 more source

Biological therapy in the treatment of melanoma [PDF]

, 2018
Melanoma is one of the most aggressive tumors and its incidence is on the rise. The low rates of survival in metastatic melanoma has led to the development of new drugs for this type of patient, such as biological therapy which has shown remarkable ...
Benea, Vasile, Georgescu, Simona Roxana, Ghita, Ela, Ioghen, Mihaela Roxana, Ion, Alexandra-Florentina, Mitran, Cristina-Iulia, Mitran, Madalina-Irina, Sarbu, Maria Isabela, Tampa, Mircea   +8 more
core   +3 more sources

Anti-programmed cell death protein-1/ligand-1 therapy in different cancers. [PDF]

, 2015
Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby promoting immune responses against several cancer types ...
Homet Moreno, B, Ribas, A
core   +2 more sources

Role of Surgery in Metastatic Melanoma and Review of Melanoma Molecular Characteristics

Cells
We aimed to review the molecular characteristics of metastatic melanoma and the role of surgery in metastasectomy for metastatic melanoma. We performed a systematic literature search on PubMed to identify relevant studies focusing on several mutations ...
Kulkaew Sukniam, Harsheen K. Manaise, Kyle Popp, Reed Popp, Emmanuel Gabriel   +4 more
doaj   +1 more source

Metastatic PRAME-Expressing Juvenile Spitzoid Melanoma on the Buttock

Case Reports in Oncology, 2020
Since the cost of molecular biological methods for Spitzoid neoplasms is expensive, the number of institutes that employ these methods might be limited. Preferentially expressed antigen in melanoma (PRAME) is a tumor-associated antigen that is useful to ...
Yusuke Muto, Taku Fujimura, Yumi Kambayashi, Kentaro Ohuchi, Ryo Amagai, Akira Hashimoto, Setsuya Aiba   +6 more
doaj   +1 more source

Anorectal Melanoma [PDF]

, 2018
Anorectal melanoma (AM) is a rare malignancy, characterized by aggressive behavior and a poor prognosis. AM is more frequent in female patients aged over 50 years.
Dario Didona, Giovanni Paolino, Giulia Macrì, Santo Raffaele Mercuri., Stefano Calvieri   +4 more
core   +1 more source

Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy

Biological Research, 2022
Background Metastatic melanoma has a high mortality rate and poor survival. This is associated with efficient metastatic colonization, but the underlying mechanisms remain elusive.
Xiaoshuang Li, Doudou Liu, Hao Chen, Bin Zeng, Qiting Zhao, Yuhan Zhang, Yuting Chen, Jianyu Wang, H. Rosie Xing   +8 more
doaj   +1 more source