Results 81 to 90 of about 284,307 (179)

Intranasal melanoma treated with radiation therapy in three dogs [PDF]

, 2017
Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L, Davies, O, Holmes, E, Lara-Garcia, A, Necova, S, Spencer, S, Taylor, A   +6 more
core   +4 more sources

Hospitalisation costs of metastatic melanoma in France; the MELISSA study (MELanoma In hoSpital coSts Assessment)

BMC Health Services Research, 2017
Background Management of metastatic melanoma is changing rapidly following the introduction of innovative effective therapies, with consequences for the allocation of healthcare resources.
Jérôme Fernandes, Bruno Bregman, Patrick Combemale, Camille Amaz, Lucie de Léotoing, Alexandre Vainchtock, Anne-Françoise Gaudin   +6 more
doaj   +1 more source

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]

, 2014
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L, Bennett, DC, Bieneck, S, Burzio, V, Fernandez, JG, Hossain, M, Leyton, L, Lobos-Gonzalez, L, Muñoz, N, Quest, AF, Silva, V, Sviderskaya, EV   +11 more
core   +2 more sources

Two synchronous lung metastases from malignant melanoma: the same patient but different morphological patterns

European Journal of Radiology Open, 2019
Malignant melanoma is an aggressive cancer with a high metastatic potential. Among the multiple sites of metastatic disease, the lung is one of the most frequently involved sites.
Andrea Borghesi, Andrea Tironi, Silvia Michelini, Alessandra Scrimieri, Diego Benetti, Roberto Maroldi   +5 more
doaj   +1 more source

Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma [PDF]

, 2020
Uveal melanoma (UM) is the most common primary eye malignancy in adults and up to 50% of patients subsequently develop systemic metastasis. Metastatic uveal melanoma (MUM) is highly resistant to immunotherapy.
Bhushan, Alok, Kaushal, Gagan, Lam, Bao, Link, Emma, Londin, Eric R, Orloff, Marlana, Rochani, Ankit, Sato, Takami, Terai, Mizue   +8 more
core   +1 more source

T Cell-Engaging Bispecific Antibodies Targeting gp100 and PRAME: Expanding Application from Uveal Melanoma to Cutaneous Melanoma

Pharmaceutics
Uveal melanoma represents a rare and aggressive subtype of melanoma with limited treatment options and poor prognosis, especially in the metastatic setting.
Robin Reschke, Alexander H. Enk, Jessica C. Hassel   +2 more
doaj   +1 more source

Single-cell transcriptomics and functional validation revealed PLEKHA5-L as a promoter of growth and migration in brain metastatic melanoma cells

Frontiers in Oncology
BackgroundMelanoma brain metastasis is an lethal event. Investigating the molecules that potentially promoted melanoma metastasis is important for targeted therapy.MethodsThe transcriptional profiles of totaling 7 melanoma samples, including 4 primary ...
Xiaogen Tang, Tingting Lei, Boya Huang, Guangjie Wu, Yizhen Tian, Jian Xiang, Dongwei Fu, Hongyi Zhang   +7 more
doaj   +1 more source

Solitary melanoma in the pineal gland: Differentiating primary from metastatic melanoma in the central nervous system

Interdisciplinary Neurosurgery
Primary melanoma of the pineal gland is exceedingly rare. Melanoma in the central nervous system (CNS) is far more likely to be a metastasis from a cutaneous primary; however, in a patient with no known history of melanoma, differentiating metastatic ...
Denesh Selvarajah, Hana Angelia Kawatu, Peter Mews, Elizabeth C Paver   +3 more
doaj   +1 more source

Melanoma Development and Progression Are Associated with Rad6 Upregulation and β-Catenin Relocation to the Cell Membrane

Journal of Skin Cancer, 2014
We have previously demonstrated that Rad6 and β-catenin enhance each other's expression through a positive feedback loop to promote breast cancer development/progression. While β-catenin has been implicated in melanoma pathogenesis, Rad6 function has not
Karli Rosner, Darius R. Mehregan, Evangelia Kirou, Judith Abrams, Seongho Kim, Michelle Campbell, Jillian Frieder, Kelsey Lawrence, Brittany Haynes, Malathy P. V. Shekhar   +9 more
doaj   +1 more source

Hypoxia-related Y RNA fragments as a novel potential biomarker for distinguishing metastatic oral melanoma from non-metastatic oral melanoma in dogs

Veterinary Quarterly
Hypoxia may promote tumor progression, and hypoxically altered noncoding RNA (ncRNA) expression may play a role in metastasis. Canine oral melanoma (COM) frequently metastasizes, and ncRNA expression under hypoxia may be clinically significant.
MD Nazmul Hasan, MD Mahfuzur Rahman, Al Asmaul Husna, Daiki Kato, Takayuki Nakagawa, Mohammad Arif, Naoki Miura   +6 more
doaj   +1 more source