Results 41 to 50 of about 42,464 (282)

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Active Metal Template Synthesis of Rotaxanes From BINOL‐Phosphate Macrocycles

Angewandte Chemie, EarlyView.
The use of macrocyclic BINOL‐phosphates allows for the active metal template synthesis of [2]rotaxanes via Cu(I)‐mediated alkyne‐azide cycloaddition. DFT calculations, control experiments, and kinetic experiments support a dinuclear phosphate‐Cu2 intermediate.
Nikolai Brodt, Sophia Stadtfeld, Somayyeh Kheirjou, Tibor Schumski, Adrian M. Bialowons, Dennis Jansen, Felix Niemeyer, Torsten Schaller, Gebhard Haberhauer, Jan Riebe, Jochen Niemeyer   +10 more
wiley   +2 more sources

Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks

Beilstein Journal of Organic Chemistry, 2013
A range of metathesis substrates was assembled from triplets of unsaturated building blocks. The approach involved the iterative attachment of a propagating and a terminating building block to a fluorous-tagged initiating building block.
Sushil K. Maurya, Mark Dow, Stuart Warriner, Adam Nelson   +3 more
doaj   +1 more source

Two‐Way Shape Memory Polymer Composite Gripper for Adaptive Robotic Applications

Advanced Materials Technologies, EarlyView.
A two‐way shape memory polymer (SMP) composite is developed with intrinsic shape‐changing capability driven solely by temperature, eliminating external actuation loads. Embedding the SMP in a low‐stiffness elastomeric matrix enabled reversible transformations during heating and cooling cycles.
Aamna Hameed, Kamran Ahmed Khan
wiley   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

Hoveyda–Grubbs catalysts with an N→Ru coordinate bond in a six-membered ring. Synthesis of stable, industrially scalable, highly efficient ruthenium metathesis catalysts and 2-vinylbenzylamine ligands as their precursors

Beilstein Journal of Organic Chemistry, 2019
A novel and efficient approach to the synthesis of 2-vinylbenzylamines is reported. This involves obtaining 2-vinylbenzylamine ligands from tetrahydroisoquinoline by alkylation and reduction followed by the Hofmann cleavage.
Kirill B. Polyanskii, Kseniia A. Alekseeva, Pavel V. Raspertov, Pavel A. Kumandin, Eugeniya V. Nikitina, Atash V. Gurbanov, Fedor I. Zubkov   +6 more
doaj   +1 more source

Backbone tuning in indenylidene-ruthenium complexes bearing an unsaturated N-heterocyclic carbene [PDF]

, 2010
The steric and electronic influence of backbone substitution in IMes-based (IMes = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene) N-heterocyclic carbenes (NHC) was probed by synthesizing the [RhCl(CO)(2)(NHC)] series of complexes to quantify ...
Slawin, Alexandra MZ, Alexandra M Z Slawin, Bantreil, Xavier, Hervé Clavier, Alexandra M. Z. Slawin, César A Urbina-Blanco, Steven P Nolan, Xavier Bantreil, Urbina-Blanco, Cesar A., Clavier, Herve, Slawin, Alexandra M. Z., César A. Urbina-Blanco, Nolan, Steven, Nolan, Steven P., Steven P. Nolan, Slawin, Alexandra M. Z.; id_orcid   +15 more
core   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Mechanochemical Defluorination of Polytetrafluoroethylene (PTFE) With Base Metals

Angewandte Chemie, EarlyView.
Polytetrafluoroethylene (PTFE) mechanochemically reacts with safe‐to‐handle, abundant, and inexpensive base metals Zn and Al, as well as with metals like Cd and Pb, to produce sp2‐carbon and industrially important metal fluorides. The reactivity presents PTFE as a mechanochemical fluorination agent, with opportunities for closed‐loop reductive ...
Anže Zupanc, A. R. Bonnie J. Lutton Gething, Alex J. Green, Shrestha Banerjee, Moosa Wasim, Luis Simbari, Benjamin B. Duff, Peter R. Slater, Dominik J. Kubicki, Erli Lu, Tomislav Friščić   +10 more
wiley   +2 more sources

Synthesis of fluorinated δ-lactams via cycloisomerization of gem-difluoropropargyl amides

Beilstein Journal of Organic Chemistry, 2010
gem-Difluoro-1,7-enyne amides are suitable building blocks for the synthesis of difluorodihydropyridinones via a ring-closing metathesis reaction, and of 4,4-difluoro-3-oxoisoquinolines through a ring-closing metathesis–enyne metathesis tandem reaction ...
Satoru Arimitsu, Gerald B. Hammond
doaj   +1 more source