Results 41 to 50 of about 544,176 (246)

Metrics from the Field: Seventeen Reasons To Do Food System Assessments

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: If the purpose of a food system is to build health, wealth, connection, and capacity in our communities, then the process of assessing food systems should also contribute to those aims.
Ken Meter
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

METRICS FROM THE FIELD: Local Data Is Endangered

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: One of the quiet impacts of the interruption of federal services in the U.S. — both the ongoing sequestration and the fall 2013 shutdown — was a tragic loss of local-level economic data.
Ken Meter
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

[News Clip: Water meter]

open access: yes, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Fort Worth installing its 100-thousandth water ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

METRICS FROM THE FIELD: Addressing Hunger by Strengthening Local Foods Logistics

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2016
First paragraphs: Las Milpitas de Cottonwood Farm in southwest Tucson is an unusual urban farm. On an intensely sandy stretch of land, bright green vegetables flourish in penetrating sunlight. Billowy clouds waft over observant mountain ridges.
Ken Meter
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Non-Intrusive Impedance Cross-Correlation (ICC) Flow Meter for Dispersed Phase Velocity and Volume Fraction Profile Measurement in Two Phase Flows [PDF]

open access: yes, 2012
This paper describes the design and implementation of an impedance cross correlation flow meter which can be used in solids-water pipe flows to measure the local solids volume fraction distribution and the local solids velocity distribution.
Lucas, Gary, Muhamedsalih, Yousif
core   +3 more sources

ANALYSIS OF THE ELECTRICITY METERING SYSTEM FOR OWN ELECTRIC SUBSTATION NEEDS

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2020
In the article the researches of the use of electronic meters with standard nominal parameters for metering of substation own electric energy in the schemes of high and low voltage networks simultaneously with the use of the corresponding calculated ...
Sergiy Stets, Andriy Stets
doaj   +1 more source

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