Results 51 to 60 of about 544,176 (246)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

The Role of Iranians in Emergence of Arabic Prosody [PDF]

open access: yesمطالعات زبانی و بلاغی, 2015
Old Arab scientists believe that prosody is a pure Arabic knowledge initiated by Khalil Ibn Ahmad, or Arabs were familiar with the poetic rhythms before the era of his life. So, they have ignored somewhat the impact of external factors.
احمد امیدوار
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

FEW-meter project data archive_01_07_2020

open access: yes, 2023
<p>Data collected in the FEW-meter project for the growing season 2020 from all case studies.
Agnès Fargue‑Lelièvre   +11 more
core   +1 more source

Influence of Musical Enculturation on Brain Responses to Metric Deviants

open access: yesFrontiers in Neuroscience, 2018
The ability to recognize metric accents is fundamental in both music and language perception. It has been suggested that music listeners prefer rhythms that follow simple binary meters, which are common in Western music.
Niels T. Haumann   +7 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

National Metrical Types in Nineteenth Century Art Song

open access: yesEmpirical Musicology Review, 2010
William Rothstein’s article “National metrical types in music of the eighteenth and early nineteenth centuries” (2008) proposes a distinction between the metrical habits of 18th and early 19th century German music and those of Italian and French music of
Leigh VanHandel
doaj   +1 more source

Nationalism and Prosody in Kurdish Poetry

open access: yesپژوهشنامه ادبیات کردی, 2020
Addressing the impact of political events on changes in metrical feet is a new approach applied in this paper. Hasanpour and Vali’s viewpoints on the history of Kurdish nationalism, the relationship between literary texts and political events, and ...
Ehsan Mardookh Rohani
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

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