Results 91 to 100 of about 8,646 (257)

Metered dose inhaler-spacer use education effects on achieve asthma control in children

, 2016
Introduction: Improper Metered Dose Inhaler (MDI)-spacer use technique can result in less than optimal delivery of medicine to the lungs and poor asthma outcomes. The aim of this study was to evaluate the influence of standardized education on proper MDI-
TÜRKELİ, AHMET, YÜKSEL, HASAN, YILMAZ, ÖZGE   +2 more
core   +1 more source

In Vitro Performance of Valved Holding Chambers in Paediatric Asthma Controller Therapy

Acta Paediatrica, EarlyView.
ABSTRACT Aim Research on the drug delivery of inhaled corticosteroids and combination medications via valved holding chambers (VHCs) with children's breathing patterns is limited. We aimed to evaluate the in vitro performance of commercially available VHCs without facemasks under preschooler breathing conditions, focusing on total delivered dose and ...
Laura Ojanperä, Lauri Lehtimäki, Péter Csonka   +2 more
wiley   +1 more source

What to consider before prescribing inhaled medications: a pragmatic approach for evaluating the current inhaler landscape

Therapeutic Advances in Respiratory Disease, 2019
Inhaled therapies are the cornerstone of treatment in asthma and chronic obstructive pulmonary disease, and there are a multitude of devices available.
Federico Lavorini, Christer Janson, Fulvio Braido, Georgios Stratelis, Anders Løkke   +4 more
doaj   +1 more source

The Agents of Climate Justice in Healthcare

Bioethics, EarlyView.
ABSTRACT This paper addresses the critical issue of decarbonising healthcare systems to help combat climate change. I focus on identifying the ‘agents of justice’ responsible for this transformation. Beginning with the claim that healthcare's greenhouse gas emissions cause injustice, the paper assumes that achieving a net zero healthcare system is ...
Joshua Parker
wiley   +1 more source

COMPARATIVE ASSESSMENT OF AERODYNAMIC PROPERTIES OF SALBUTAMOL PRESSURIZED METERED DOSE INHALERS

Разработка и регистрация лекарственных средств, 2019
The aerodynamic properties of the developed generic product Salbutamol metered dose inhaler 100 μg/dose and Salbutamol-Teva metered dose inhaler 100 μg/dose using apparatuses A, C, D and E in accordance with the general article 2.9.18 of the European ...
N. A. Lyapunov, E. P. Bezuglaya, V. A. Bovtenko, Yu. M. Stolper   +3 more
doaj  

A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD

, 2019
International audienceGlycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI), formulated using co-suspension delivery technology, is the only approved fixed-dose combination long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA ...
Bourdin, Arnaud, Jenkins, M.A., Feldman, G.J., Deslée, Gaetan, Ferguson, Gary, Martin, U.J., Fjällbrant, Harald, Maltais, François, Siwek-Posłuszna, Agnieszka   +8 more
core   +1 more source

Influence of Actuator Nozzle Angle on the Flow Characteristics in Pressurized-Metered Dose Inhaler Using CFD

, 2020
Pressurized metered dose inhalers (pMDIs) are often used for the treatment of asthma and chronic obstructive pulmonary disease. This device is easy to carry, highly effective and extremely safe, allowing reliable, consistent dosage delivery, metered dose
Asmuin, Nor Zelawati, Hidayat Mat, Mohamad Nur, Abd Rahman, Muhammad Faqhrurrazi, Taib, Ishkrizat, Khairulfuaad, Riyadhthusollehan   +4 more
core   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Effect of education on proper use of metered-dose inhaler

, 2000
의학과/석사[한글] 정량 흡입기 (Metered-dose inhaler)는 기도질환 환자 치료에 있어 필수 불가결한 치료 방법으로 이용되고 있으나 사용시 흡입기를 누르는 시점과 흡입의 시점이 정확히 일치하여야 하고, 흡입속도를 천천히 지속적으로 하여야 하며, 폐활량에도 영향을 받는 등 문제점이 있어서 사용법에 대한 정확한 교육이 필요하다.
최승원
core  

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source