Results 141 to 150 of about 8,646 (257)

Spinal Implant–Associated Infection in Type 2 and Type 1 Diabetes: Phenotype‐Specific Inflammatory Features and Therapeutic Response to Semaglutide

JOR SPINE, Volume 9, Issue 2, June 2026.
ABSTRACT Background Diabetes mellitus (DM) is a major risk factor for postoperative infection and wound complications in spine surgery, yet distinctions between Type 2 (T2DM) and Type 1 (T1DM) pathophysiology are rarely addressed. This study compares infectious burden, wound healing, and immune response among a murine model of spinal implant‐associated
Thomas E. Olson, Trevor S. Lloyd, Christopher D. Hamad, Rene F. Chun, Joshua Wiener, Autreen Golzar, Joshua Mehany, Soroush Shahamatdar, Andrew Kittredge, Lauren Pearce, Kevin P. Francis, Farres Obeidin, Langston T. Holly, Michael R. Yeaman, John S. Adams, Nicholas M. Bernthal, William L. Sheppard   +16 more
wiley   +1 more source

A novel method of metered-dose inhaler delivery in intubated COVID-19 patients. [PDF]

Saudi J Anaesth, 2022
Mustahsin M, Singh G, Choubey S.
europepmc   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Oral inhalation of cannabidiol delivered from a metered dose inhaler to alleviate cytokine production induced by SARS-CoV-2 and pollutants. [PDF]

J Drug Deliv Sci Technol, 2022
Srichana T, Chunhachaichana C, Suedee R, Sawatdee S, Changsan N.   +4 more
europepmc   +1 more source

Preclinical Quantitative In Vivo MRI Assessment of Exogenous Surfactant Pulmonary Distribution After Clinically Relevant Intratracheal Delivery

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Quantitative in vivo contrast‐enhanced UTE MRI enables sensitive and precise mapping of pulmonary surfactant distribution, revealing peripheral localization and homogeneous distal penetration under physiological conditions. Comparison with ex vivo models highlights the role of physiological processes in surfactant retention.
Oumaima Marfouk, Rémy Gérard, Ghalia Kaouane, Lara Leclerc, Noël Pinaud, Michael Fayon, Sophie Périnel‐Ragey, Jérémie Pourchez, Eric Dumas De La Roque, Yannick Crémillieux   +9 more
wiley   +1 more source

Utility of a Mask with a Spacer to Deliver the Contents of a Metered Dose Inhaler. [PDF]

Ann Am Thorac Soc, 2021
Tualzik L, Chandrasekaran V.
europepmc   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Reply: Utility of a Mask with a Spacer to Deliver the Contents of a Metered Dose Inhaler. [PDF]

Ann Am Thorac Soc, 2021
Volerman A, Balachandran U, Siros M, Akel M, Press VG.   +4 more
europepmc   +1 more source

Investigate flow characteristics of Metered-Dose Inhaler (MDI) Disposable Inhaler Spacer (AeroCup) for COVID-19 patient by using Computational Fluid Dynamic (CFD)

, 2020
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory coronavirus 2 syndrome (SARS-CoV-2) were first reported by officials in Wuhan City, China, in December 2019.
Asmuin, Nor Zelawati, Nazar, Juwaidi, Abd Rahman, Muhammad Faqhrurrazi, Taib, Ishkrizat, Khairulfuaad, Riyadhthusollehan, Ismail, Azizan   +5 more
core  

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source