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Nonprescription Epinephrine Metered-Dose Inhaler: To Be or Not To Be
Pediatric Allergy, Immunology, and Pulmonology, 2014A new product, Epinephrine HFA, is being considered by the Food and Drug Administration (FDA) for marketing approval as a nonprescription bronchodilator inhaler for the treatment of the “temporary relief of mild symptoms of intermittent asthma in adults and children 12 years of age and older.” This product would serve as a ...
Kathryn, Blake, Hengameh, Raissy
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The Continued Need for Metered Dose Inhalers
Journal of Aerosol Medicine, 1995The metered dose inhaler (MDI) is currently the most widely used device in the treatment of adult asthma. It is the delivery system of choice in general practice throughout the world where both MDIs and powder inhalers are available. Up to 70% of all UK adult asthma prescriptions are for an MDI and worldwide the figures are likely to be higher. The MDI
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Inability of Physicians to Use Metered-Dose Inhalers
Journal of Asthma, 1997The effectiveness of antiasthmatic therapy with metered-dose inhalers (MDIs) is usually limited by defective inhalational technique. This study surveyed the MDI inhalation performance and knowledge of 100 physicians whose performance (demarcated into six stages) and knowledge scores correlated (r = 0.33, p < 0.001).
Ip, M +8 more
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Spacer Devices for Metered Dose Inhalers
Clinical Pharmacokinetics, 2004Spacer devices are attachments to the mouthpieces of pressurised metered dose inhalers (pMDIs), and range from tube spacers with a volume of
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Principles of Metered-Dose Inhaler Design
Respiratory Care, 2005The pressurized metered-dose inhaler (pMDI) was introduced to deliver asthma medications in a convenient and reliable multi-dose presentation. The key components of the pMDI device (propellants, formulation, metering valve, and actuator) all play roles in the formation of the spray, and in determining drug delivery to the lungs.
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Metered-Dose Inhalers, Dry Powder Inhalers, and Transitions
Respiratory Care, 2000Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology.
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Pressurized Metered-Dose Inhalers
2019Pressurized Metered-dose Inhalers (pMDIs) are complex drug-device combination products that are widely used to treat lung diseases, and may also be advantageously employed to deliver active pharmaceutical ingredients (APIs) to the systemic circulation through the lungs. pMDIs occupy ca.
Sandro R.P. da Rocha +3 more
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