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Spacer Devices for Metered Dose Inhalers
Clinical Pharmacokinetics, 2004Spacer devices are attachments to the mouthpieces of pressurised metered dose inhalers (pMDIs), and range from tube spacers with a volume of
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Principles of Metered-Dose Inhaler Design
Respiratory Care, 2005The pressurized metered-dose inhaler (pMDI) was introduced to deliver asthma medications in a convenient and reliable multi-dose presentation. The key components of the pMDI device (propellants, formulation, metering valve, and actuator) all play roles in the formation of the spray, and in determining drug delivery to the lungs.
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Metered-Dose Inhalers, Dry Powder Inhalers, and Transitions
Respiratory Care, 2000Since 1956, the pMDI has become the most commonly prescribed and used aerosol device in the world. While concerns about global warming have led to a worldwide ban of CFCs, new HFA-propelled pMDIs are in development, requiring an evolutionary transition in the technology.
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Pressurized Metered-Dose Inhalers
2019Pressurized Metered-dose Inhalers (pMDIs) are complex drug-device combination products that are widely used to treat lung diseases, and may also be advantageously employed to deliver active pharmaceutical ingredients (APIs) to the systemic circulation through the lungs. pMDIs occupy ca.
Sandro R.P. da Rocha +3 more
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Compatibility of spacers with metered-dose inhalers
American Journal of Health-System Pharmacy, 2001R E, Lakamp +3 more
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