Results 31 to 40 of about 8,646 (257)

Inhaler Competence in Nepalese Patients with Asthma and Chronic Obstructive Pulmunory Disease: A Systematic Review

Journal of Nepal Health Research Council, 2022
Background: Incorrect use of inhalers in patients with asthma and chronic obstructive pulmonary disease is prevalent internationally. This review aims to determine the prevalence and associated factors of incorrect inhaler use and effectiveness of ...
Ramesh Sharma Poudel, Shakti Shrestha, Daniel Asfaw Erku, Praves Lamichhane, Sharad Karki, Dipesh Maskey, Shital Adhikari   +6 more
doaj   +1 more source

Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations. A real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation

, 2011
Background Although patients have more problems using metered dose inhalers, clinical comparisons suggest they provide similar control to dry powder inhalers.
Eszes, Noemi, Gabriele Nicolini, Chrystyn, Henry, Eszes Noemi, György Losonczy, Noemi Eszes, Henry Chrystyn, Müller, Veronika, Gabriella Gálffy, Chrystyn Henry, Nicolini Gabriele, Gálffy Gabriella, Andrea Bizzi, Lilla Tamási, Bizzi Andrea, Tamási Lilla, Gálffy, Gabriella, Tamási, Lilla, Müller Veronika, Losonczy, György, Nicolini, Gabriele, Bizzi, Andrea, Veronika Müller, Losonczy György   +23 more
core   +1 more source

Penjelasan Cara Penggunaan Inhaler Ipratropium Bromida oleh Apoteker

Keluwih, 2022
—MDI (metered-dose inhaler) containing Ipratropium Bromide is used to control COPD symptoms. Improper use can trigger unwanted effects, so it takes the role of pharmacists in helping explain how to use it.
Amelia Lorensia, Dea Amelia Aditya Winata   +1 more
doaj   +1 more source

Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control

, 2009
Background As more inhaled corticosteroid (ICS) devices become available, there may be pressure for health-care providers to switch patients with asthma to cheaper inhaler devices. Our objective was to evaluate impact on asthma control of inhaler device
Williams, Angela E., Chrystyn, Henry, von Ziegenweidt Julie, Andrew Lloyd, Thomas, Mike, Mike Thomas, Henry Chrystyn, Angela E Williams, Lloyd, Andrew, Chrystyn Henry, von Ziegenweidt, Julie, Price David, Price, David, Julie von Ziegenweidt, Thomas Mike, Lloyd Andrew, Williams Angela E, David Price   +17 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Estimation of Particle Deposition in the Airways from Different Inhaler Formulations Using an In Silico Model

KONA Powder and Particle Journal, 2014
The objective of these studies was to evaluate the use of an in silico model for predicting lung deposition of inhaled therapeutic aerosols.
Hugh D.C. Smyth, Ted B. Martonen, Kristin K. Isaacs, Anthony J. Hickey   +3 more
doaj   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

New formulation metered dose inhaler increases breath alcohol levels

, 1999
A new, chlorofluorocarbon-free metered dose inhaler containing salbutamol, with small amounts of ethanol as a co-solvent, has recently been released. We evaluated the effect on breath alcohol levels of two inhalations from this metered dose inhaler.
O'Callaghan, C., Barry, P.W.
core   +1 more source

Hair analysis of formoterol as a novel tool to assess long‐term inhalation medication adherence: Data from the TRICOLON trial

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this paper is to examine inhaled formoterol concentrations in hair and assess the potential of hair analysis as a tool for measuring long‐term adherence, by validation with objective data from digital inhalers. Methods Hair samples and digital inhaler data were collected from patients with COPD in 10 hospitals in the Netherlands as part ...
Liz J. A. Cuperus, A. Mireille A. Wessels, Huib A. M. Kerstjens, Daan J. Touw, Erik W. M. A. Bischoff, Job van der Palen, Arnoud Aldenkamp, Astrid van Huisstede, Folkert Brijker, Stephan Dik, Lidwien Graat‐Verboom, Martijn Goosens, Peter Th. W. van Hal, Jolanda C. Kuijvenhoven, Lisette I. Z. Kunz, Renske van der Meer, Mariette H. A. Scholma‐Bronsema, Job F. M. van Boven, Johannes C. C. M. in't Veen, the TRICOLON study group, Marjo van der Poel, Irini Piso, Marijke Amelink, Anke Rol, Jennifer de Graaf, Petra Hirmann, Fleur van Tour, Elly Jordens, Lydia Alfing, Gerda Lenderink, Truus Rietveld, Jasmijn van Campen, Jantine de Bruijn, Janice van ter Burg, Liselore Baarssmit, Walter van Litsenburg, Len Knoops, Margot Eggermont‐Schilt, Manon de Waard‐Heijligers, Ilonka Paalvast‐Schouten, Mariette Scholma, Sandra Brookman‐Mozes, Inge Paas, Lidwien Verboom, Karin van Mierlo‐Snoeijs   +44 more
wiley   +1 more source