Results 41 to 50 of about 8,646 (257)

Shape Memory Alloy Actuation of a Metered-Dose Inhaler

open access: yes, 2017
Respiratory diseases such as asthma or chronic obstructive pulmonary disorder (COPD) affect millions of people around the world. The most common treatment approach is to take an inhaled corticosteroid as needed with a dry-powder inhaler or a metered-dose
Brent Utter, Leslie Weaver
core   +1 more source

Goal Displacement and Goal Conflicts in Circular Innovation Initiatives: Types and Mitigation Practices

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim   +2 more
wiley   +1 more source

Impact of an education program on knowledge, metered-dose inhaler technique among asthma patients in a tertiary care hospital

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Inhalers are most often prescribed to asthma patients and patients need to inhale correctly and coordinate breathing and actuation to ensure effective drug delivery.
Roopavathy G M, Praveen Panchaksharimath
doaj   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

open access: yesChemistry – A European Journal, EarlyView.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande   +6 more
wiley   +1 more source

Comparison of the efficacy of budesonide by nebulizer, metered dose inhaler and dry powder inhaler in chronic stable bronchial asthma

open access: yes, 2018
Background: The study has been performed to evaluate the efficacy of budesonide delivery by different form of devices like nebulizer, metered dose inhaler and dry powder inhaler to adult patients of chronic stable bronchial asthma.
Rizvi, Dilshad Ali   +3 more
core   +1 more source

Elimination Profile of Deflazacort and Metabolites in Urine and Plasma Following Oral Administration: Relevance to Sports Drug Testing

open access: yesDrug Testing and Analysis, EarlyView.
Results confirm that the MRL of 30 ng/mL for 21‐desacetyl‐deflazacort together with a 3‐day washout period is an appropriated strategy to detect oral deflazacort administration in sport competition. ABSTRACT Deflazacort (DEF) is a glucocorticoid prohibited in sports competitions when orally administered.
Sergi Coll   +5 more
wiley   +1 more source

On the Bibliometric Profile of Metered Dose Inhaler Research

open access: yesMedical Sciences Forum, 2022
Pulmonary drug delivery systems (PDDS) have gained particular attention of pharmaceutical scientists due to their potency in the therapy of both pulmonary diseases and systemic diseases.
Lei Shu   +4 more
doaj   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

The comparative effectiveness and safety of fluticasone-salmeterol via metered-dose versus dry powder inhalers for COPD: A new user cohort study.

open access: yesPLoS Medicine
BackgroundFluticasone-salmeterol is available in both metered-dose and dry powder inhaler formulations for the treatment of chronic obstructive pulmonary disease (COPD).
Brandon J Demkowicz   +4 more
doaj   +1 more source

The Inhalation Characteristics of Patients When They Use Different Dry Powder Inhalers

open access: yes, 2015
Background: The characteristics of each inhalation maneuver when patients use dry powder inhalers (DPIs) are important, because they control the quality of the emitted dose.
Stephenson, John   +6 more
core   +1 more source

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