Results 131 to 140 of about 6,051 (258)

Benchmarking Hybrid CNN‐Transformer Versus Pure Transformer Architectures for Accelerated Hyperpolarized 129Xe MRI Reconstruction

Journal of Magnetic Resonance Imaging, Volume 64, Issue 1, Page 266-280, July 2026.
ABSTRACT Background Hyperpolarized 129Xe MRI faces technical challenges including low signal‐to‐noise ratio and breath‐hold constraints. Current literature focuses on proprietary deep learning methods or image‐domain enhancements. Purpose To present a comprehensive evaluation of transformer and hybrid CNN‐transformer architectures integrating dual ...
Ramtin Babaeipour, Matthew S. Fox, Grace Parraga, Alexei Ouriadov   +3 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Systematic Evaluation of the Effect of Formulation Variables on In Vitro Performance of Mometasone Furoate Suspension-Metered Dose Inhalers. [PDF]

AAPS J, 2021
Bachhav SS, Sheth P, Sandell D, Svensson M, Bhagwat S, Conti DS, Oguntimein O, Dhapare S, Saluja B, Winner L, Bulitta JB, Hochhaus G.   +11 more
europepmc   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3866-3884, July 2026.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero, Brigida Boccanegra, Paola Mantuano, Antonietta Mele, Michela De Bellis, Roberta Lenti, Francesca Sanarica, Santa Cirmi, Elena Conte, Ornella Cappellari, Amber E. Sherrard, Ardawna Green, Mira Srinivasa, Marta L. Fiorotto, Annamaria De Luca   +14 more
wiley   +1 more source

Use of Assist Devices to Actuate Pressurized Metered-Dose Inhalers in Elderly Patients with Asthma. [PDF]

Pulm Ther, 2021
Hirose M, Kondo R, Horiguchi T.
europepmc   +1 more source

Pressurised metered-dose inhalers: How do they work? A short guide for clinicians.

Pressurised metered-dose inhalers (pMDIs) are widely used in the treatment of paediatric respiratory diseases. Despite their widespread use, knowledge about effective inhaler technique amongst patients and clinicians is poor.
Beckett, Robert S, Carroll, William D, Gilchrist, Francis J, Fairbrother, Chloe B, Rubin, Bruce K   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Parental Perception About Metered-Dose Inhalers and Nebulizers Differences Among Saudi Arabia. [PDF]

Cureus, 2021
Alzayed AA, Alotaibi AS, Alfadhli RF, Alageel RA, Al-Saqat WS, Alghadeer HA.   +5 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, Volume 13, Issue 35, 24 June 2026.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

An Intervention Study of Pharmacists’ Knowledge and Patient Counseling on Metered Dose Inhalers and Nebulizers

, 2020
To carry out an intervention study on pharmacists’ knowledge on metered dose inhalers (MDIs) and nebulizers, and patient counseling on MDIs in a tertiary hospital in South-Western Nigeria.
Aje, A.A, Aina, O.A
core